Background: The fractionated nonablative 1440-nm laser creates microscopic thermal wounds within the epidermis and the dermis and is used clinically to improve tone, texture, and color of skin.
Objective: We sought to investigate the use of this device to treat facial pores and to improve skin texture.
Methods: Twenty patients received 6 treatments at the highest tolerable energy level performed 2 weeks apart. Photographic assessments using the VISIA-CR (Canfield Scientific Inc, Fairfield, NJ) imaging system were performed. The pore score was calculated, which is the percentage of the skin surface that has detected pores. Subjective measurements (0-4 scale) were recorded by both the subject and investigator regarding pore appearance, skin texture, and overall skin appearance. Treatment discomfort was scored by patients (1-10 scale).
Results: After 6 treatments there was a significant reduction in pore score (P < .002). Total average pore score at baseline was 2.059 ± 0.8 and 2 weeks after the final treatment it was 1.700 ± 0.8, resulting in a 17% average reduction in pore score. Study investigators reported average scores being 1.95 ± 0.3 for improved pore appearance and 2.75 ± 0.2 for improved overall appearance (0-4 scale). Subjects noted average scores of 1.9 ± 0.5 for improvement of the appearance of pores and 2.85 ± 0.4 for improvement of overall appearance (0-4 scale). The average discomfort score during treatments was reported to be 4.6 ± 0.1 (1-10 scale). There were no serious adverse effects or long-term side effects.
Limitations: Small sample size and limited follow-up are study limitations.
Conclusions: A series of treatments with the nonablative low-energy fractional 1440-nm laser appears to be safe and effective for reducing detectable pores and improving overall skin appearance.
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http://dx.doi.org/10.1016/j.jaad.2012.08.041 | DOI Listing |
PLoS One
January 2025
Genome and Structural Bioinformatics Group, Faculty of Medicine, Health and Life Science, Swansea University, Swansea, Wales, United Kingdom.
Aquaporin 1 (AQP1) is a key channel for water transport in peritoneal dialysis. Inhibition of AQP1 could therefore impair water transport during peritoneal dialysis. It is not known whether inhibition of AQP1 occurs unintentionally due to off-target interactions of administered medications.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Civil Engineering Department, Lanzhou Jiaotong University, Lanzhou 730070, China.
This study investigates the effect of microstructural changes in polyurethane coatings on their water resistance properties. Polyurethane coatings with varying diluent contents were prepared and tested for water penetration resistance and mechanical property retention. The time-dependent behavior of water within the coatings at different immersion durations was analyzed using low-field nuclear magnetic resonance (NMR).
View Article and Find Full Text PDFBiomater Transl
September 2024
Orthopaedic Research Institute and Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Three-dimensional printed Ti-6Al-4V hemipelvic prosthesis has become a current popular method for pelvic defect reconstruction. This paper presents a novel biomimetic hemipelvic prosthesis design that utilises patient-specific anatomical data in conjunction with the Voronoi diagram algorithm. Unlike traditional design methods that rely on fixed, homogeneous unit cell, the Voronoi diagram enables to create imitation of trabecular structure (ITS).
View Article and Find Full Text PDFFoods
November 2024
Guangxi Key Laboratory of Health Care Food Science and Technology, Hezhou University, Hezhou 542899, China.
This study focused on persimmons and applied variable-temperature pressure-differential puffing drying to produce persimmon chips. The effects of puffing pressure, holding time, drying temperature, and duration on moisture content, crispness, and sensory scores were examined. The optimal parameters determined via response surface methodology were a pressure differential of 0.
View Article and Find Full Text PDFHernia
December 2024
Hernia Center, Vivantes Humboldt Hospital, Academic Teaching Hospital of Charité University Medicine, Am Nordgraben 2, 13509, Berlin, Germany.
Introduction: In inguinal hernia repair, mesh weight and pore size are used to describe the mesh characteristics. One meta-analysis of laparo-endoscopic inguinal hernia repairs identified 12 prospective randomized controlled trials (RCTs) with 2,909 patients who had all been treated with lightweight (≤ 50 g/m²) or heavyweight (> 70 g/m²) meshes. None of the 12 RCTs gave details of the pore size.
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