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Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint.
Front Artif Intell
January 2025
General Thoracic Surgery, General Hospital of Ningxia Medical University, Yinchuan, China.
Introduction: Tumor heterogeneity significantly complicates the selection of effective cancer treatments, as patient responses to drugs can vary widely. Personalized cancer therapy has emerged as a promising strategy to enhance treatment effectiveness and precision. This study aimed to develop a personalized drug recommendation model leveraging genomic profiles to optimize therapeutic outcomes.
View Article and Find Full Text PDFThree-dimensional printed anatomical models as an educational tool for orthopaedic surgical trainees - A single institution experience.
J Clin Orthop Trauma
March 2025
Department of Orthopaedic Surgery, Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, Singapore, 308433, Singapore.
Objective: To evaluate the utility of three-dimensional (3D) anatomical models as an educational tool among Orthopaedic surgical trainees.
Methods: Seven types of 3D anatomical models - humerus, elbow, ankle, calcaneum, knee, femur, and pelvis- based on patients' computational tomography (CT) scans were printed in the study institution and used by surgical trainees preoperatively. Responses were collected in the form of a Likert scale questionnaire.
Massive Periacetabular Osteolysis Treated With Acetabular Cup Retention and Cemented Screw Fixation.
Arthroplast Today
February 2025
Department of Orthopaedic Surgery, University of California, San Diego, San Diego, CA, USA.
Management of periacetabular osteolysis is a challenging dilemma in revision total hip arthroplasty. When the acetabular shell is well-fixed, the surgeon may prefer to retain the cup to minimize further bone loss. However, filling the surrounding defect can be difficult if the area of involvement is massive.
View Article and Find Full Text PDFEffects of transcutaneous electric nerve stimulation on pain after episiotomy. A systematic review and meta-analysis.
Heliyon
January 2025
Faculty of Physiotherapy, University of Vigo, Pontevedra, Spain.
Background: Episiotomy is a surgical intervention performed during the second stage of labor to facilitate the baby's exit through the birth canal. There are different reasons that lead episiotomy; however, it is recommended performed occasionally and not systematically, since it may produce negative effects such as pain. Different therapies have been described to reduce this pain, including transcutaneous electrical nerve stimulation (TENS).
View Article and Find Full Text PDFEnhancing Patient Choice Through the Development of Physical Therapist Online Biographies.
J Patient Exp
January 2025
Purdue University Student Health Services, West Lafayette, IN, USA.
Provider web profiles are becoming popular locations for patients to seek information before their visits. This industry insight assesses patients' utilization of a physical therapy clinic's website to determine the impact the addition of physical therapist biographies had on patient perceptions and physical therapist selection. Forty-six percent of first-time patients ( = 786) indicated visiting the clinic's website prior to their visit.
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