AI Article Synopsis
- A severe outbreak of respiratory infections occurred in two orphanages in Vietnam, resulting in the hospitalization of children and a high mortality rate (7 out of 12 children died).
- Testing showed that a significant majority (26 out of 43) of children from the affected orphanages were positive for rhinovirus, compared to only 9 out of 40 control children, indicating a strong association with the outbreak (p = 0.0005).
- The specific rhinoviruses linked to the outbreak formed a unique genetic cluster, highlighting that rhinovirus can be a serious cause of pneumonia, especially in vulnerable populations like orphaned children.
Article Abstract
During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. Human rhinovirus is an underappreciated cause of severe pneumonia in vulnerable groups.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559162 | PMC |
| http://dx.doi.org/10.3201/eid1811.120607 | DOI Listing |
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