The heliotherapy and the phototherapy are mainly focused on taking benefit of the therapeutic effects of the ultraviolet (UV) irradiance on different skin diseases. The use of UV-B narrowband lamps, with emissions centered at 311 nm, has spread out among the dermatologist community because of its high therapeutic effect in comparison with its low erythema dose. For cloudless sun exposure, the balance of solar erythemal and solar narrowband (NB)-equivalent irradiances depends on several factors such as the solar zenith angle (SZA), the total ozone column (TOC) and the altitude. For SZA below 55°, the ratio of solar UV-B narrowband and erythemal irradiances increases with the SZA whereas the ratio of vitamin D production and erythemal irradiances decreases with the SZA with the maximum around midday. Furthermore, the solar NB ratio also increases with the TOC because the shorter wavelengths of the erythemal action spectrum are more affected by the ozone absorption processes. Considering the daily variations of the ratio between narrowband and erythemal irradiance, sun exposures avoiding midday hours are recommended in order to prevent negative side-effects. However to accumulate great NB doses and sufficient vitamin D in winter months is difficult because the time exposures may be longer than the day duration.
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http://dx.doi.org/10.1016/j.jphotobiol.2012.09.004 | DOI Listing |
Clin Cosmet Investig Dermatol
December 2024
Department of Dermatology, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Background: Vitiligo is a chronic autoimmune disease manifested by depigmented patches of skin devoid of melanocytes. Baricitinib, a JAK inhibitor selectively targeting JAK1/2, has shown preliminary efficacy for vitiligo. We aimed to assess the efficacy and tolerability of combination therapy with baricitinib and narrowband UV-B (NB-UVB) to treat active nonsegmental vitiligo (NSV).
View Article and Find Full Text PDFJAMA Dermatol
December 2024
Department of Dermatology, University of Utah School of Medicine, Salt Lake City.
Heliyon
August 2024
Department of Physics, University of Johannesburg, Johannesburg, South Africa.
Apart from the use of sun therapy for the cure of many skin diseases and disorders of bygone days, nowadays artificial light sources of a narrowband (NB) ultraviolet-B (UV-B) have effectively revolutionized the treatment of such skin diseases. The crucial role of gadolinium (Gd) ions in calcium-based hosts lies in their narrowband emission spectrum, specifically at 311-315 nm, attributed to the P to S transition. Calcium-based materials, known for their chemical stability, facilitate Gd embedding, enabling UV activation and express emission in the narrowband range.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
January 2025
Department of Dermatology, Venereology and Leprosy, Government Stanley Hospital, Chennai, India.
JAAD Case Rep
July 2024
Department of Dermatology, University of Massachusetts Chan Medical School, Worcester, Massachusetts.
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