Background/aims: The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC).
Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied.
Results: The HLA-B35 was significantly increased in TRC group (p=0.0038).
Conclusion: The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810704 | PMC |
| http://dx.doi.org/10.3233/DMA-2012-00935 | DOI Listing |
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