The effect of the recently developed graphene nanoflakes (GNFs) on the polymerase chain reaction (PCR) has been investigated in this paper. The rationale behind the use of GNFs is their unique physical and thermal properties. Experiments show that GNFs can enhance the thermal conductivity of base fluids and results also revealed that GNFs are a potential enhancer of PCR efficiency; moreover, the PCR enhancements are strongly dependent on GNF concentration. It was found that GNFs yield DNA product equivalent to positive control with up to 65% reduction in the PCR cycles. It was also observed that the PCR yield is dependent on the GNF size, wherein the surface area increases and augments thermal conductivity. Computational fluid dynamics (CFD) simulations were performed to analyze the heat transfer through the PCR tube model in the presence and absence of GNFs. The results suggest that the superior thermal conductivity effect of GNFs may be the main cause of the PCR enhancement.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1088/0957-4484/23/45/455106 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Entropy performance of nonlinear mathematical hydrocarbon based model using ternary alloys (AA7072/AA7075/TiAIV) under influential solar radiations and convective effects.
Sci Rep
December 2024
Department of Physics, Laghman University, Mehtarlam City, Laghman, 2701, Afghanistan.
Aluminum alloys have promising characteristics which make them more useful in industrial applications for thermal management and entropy of the fluidic system. Hence, the current research deals with the analysis of entropy and thermal performance of (CHO-HO)/50:50% saturated by (AA7072/AA7076/TiAIV) alloys. Traditional problem modified using enhanced characteristics of ternary alloys and hydrocarbon 50:50% base fluid.
View Article and Find Full Text PDFFirst-principles calculations to investigate thermoelectric, thermophysical, and optical properties of RNi₄P₁₂ (R = Sm, Eu) rare-earth metal skutterudites.
Sci Rep
December 2024
Condensed Matter Theory Group, School of Studies in Physics, Jiwaji University, Gwalior, 474 011, India.
This study presents a comprehensive investigation into the intrinsic properties of RNiP (where R = Sm, Eu) filled skutterudite, employing the full-potential linearized augmented plane wave method within density functional theory (DFT) simulations using the WIEN2k framework. Structural, phonon stability, mechanical, electronic, magnetic, transport, thermal, and optical properties are thoroughly explored to provide a holistic understanding of these materials. Initially, the structural stability of SmNiP and EuNiP is rigorously evaluated through ground-state energy calculations obtained from structural optimizations, revealing a preference for a stable ferromagnetic phase over competing antiferromagnetic and non-magnetic phases.
View Article and Find Full Text PDFUltralow k covalent organic frameworks enabling high fidelity signal transmission and high temperature electromechanical sensing.
Nat Commun
December 2024
Key Laboratory of Advanced Polymeric Materials of Shanghai, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, P. R. China.
As integrated circuits have developed towards the direction of complexity and miniaturization, there is an urgent need for low dielectric constant materials to effectively realize high-fidelity signal transmission. However, there remains a challenge to achieve ultralow dielectric constant and ultralow dielectric loss over a wide temperature range, not to mention having excellent thermal conductivity and processability concurrently. We herein prepare dual-linker freestanding covalent organic framework films with tailorable fluorine content via interfacial polymerization.
View Article and Find Full Text PDFAdvancing characterization of pyrolysis products: Comprehensive gas chromatography methods for analytes in gas and liquid phases.
J Chromatogr A
December 2024
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5. Electronic address:
The development of biofuel technologies depends on the accurate identification and quantification of products from the conversion processes. Given the complexity of the renewable resources, the availability of biomass, and the versatility of conversion methods, there is a need for characterization methods that provide rapid and reliable analysis for various products coming from different conversion processes with minimal sample preparation. This study develops and validates gas chromatography methods that use multiple detectors to analyze pyrolytic compounds in both gas and liquid phases efficiently in a single, rapid run.
View Article and Find Full Text PDFThermal management of photovoltaic module using affordable organic phase change material combined with nano metal oxide particles enhancer.
Heliyon
December 2024
Mechanical Engineering Division, Faculty of Engineering, Khon Kaen University, Thailand.
Phase change materials (PCMs) have been widely recognized as a highly efficient medium for thermal energy storage. Many studies have identified the low thermal conductivity of PCMs. In the current investigation, the researchers have blended PCM with nanoparticles to enhance its thermal conductivity and electrical efficiency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!