Objective: The objective of this study was to compare the psychological changes of patients with cleft lip and palate (CLP) undergoing maxillary Le Fort I advancement by distraction osteogenesis (DO) and conventional orthognathic surgery (CO).
Study Design: Prospective randomized controlled study. Participants completed a set of questionnaires to measure their psychological states preoperatively and postoperatively.
Result: When compared with CO, CLP patients treated with DO had lower social self-esteem and higher social avoidance and distress levels during the first 3 postoperative months. Their self-esteem, social avoidance, and distress levels improved after the distractors were removed. Both CO and DO patients had similar levels of self-esteem, social avoidance, and distress levels 2 years postoperatively. The CLP patients treated with DO were more satisfied with their lives after 2 years.
Conclusions: DO may induce short-term distress to patients up to 3 months but CLP patients who received DO were more satisfied with their lives in the long term.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.tripleo.2011.07.047 | DOI Listing |
J Inflamm (Lond)
January 2025
Department of Critical Care Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China.
Background: Sepsis is a severe condition causing organ failure due to an abnormal immune reaction to infection, characterized by ongoing excessive inflammation and immune system issues. Osteopontin (OPN) is secreted by various cells and plays a crucial role in inflammatory responses and immune regulation. Nonetheless, the precise function of OPN in sepsis remains to be elucidated.
View Article and Find Full Text PDFInt Dent J
January 2025
Manav Rachna International Institute of Research and Studies(MRIIRS), Faridabad, India; Department of Conservative Dentistry and Endodontics, Manav Rachna Dental College, Faridabad, India.
Background: Cleft lip with/without palate (CL/P) patients require multiple interdisciplinary procedures at different phases of their life. CL/P patients have a high burden of care that has financial repercussion, especially in low- and middle-income countries (LMICs). Lowering preventable diseases such as caries can mitigate this challenge.
View Article and Find Full Text PDFMol Oncol
January 2025
Department of Gastrointestinal Cancer Translational Research, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.
Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide, with gastrectomy being the primary treatment option. Sepsis, a systemic inflammatory response to infection, may influence tumor growth by creating an immunosuppressive environment conducive to cancer cell proliferation and metastasis. Here, the effect of abdominal infection on tumor growth and metastasis was investigated through the implementation of a peritoneal metastasis model and a subcutaneous tumor model.
View Article and Find Full Text PDFCrit Care
January 2025
Department of Critical Care Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.
Background: Phospholipid transfer protein (PLTP), a glycoprotein widely expressed in the body, is primarily involved in plasma lipoprotein metabolism. Previous research has demonstrated that PLTP can exert anti-inflammatory effects and improve individual survival in patients with sepsis and endotoxemia by neutralizing LPS and facilitating LPS clearance. However, the role of PLTP in sepsis-associated acute kidney injury (SA-AKI) and the specific mechanism of its protective effects are unclear.
View Article and Find Full Text PDFBMJ Open
January 2025
Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Abo, Finland.
Background: The patient safety climate in community pharmacies was measured nationally in Sweden in 2008. Since that time the Swedish pharmacy market has undergone a re-regulation which probably has affected the patient safety climate in pharmacies.
Objectives: The aim was to evaluate the patient safety climate among pharmacists working in Swedish community pharmacies and compare it with historical data.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!