Hedgehog signaling is transduced at the primary cilium, but the precise mechanisms underlying this action are not clear. In this issue of Developmental Cell, Dorn and colleagues (2012) describe a novel mechanism for control of Hedgehog signaling by Evc proteins within the primary cilium.
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| http://dx.doi.org/10.1016/j.devcel.2012.10.001 | DOI Listing |
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