A 10-year-old female domestic shorthair cat that had been neutered 9 years earlier was presented with unspecific symptoms (weight loss, vomiting). As an underlying reason a uterine lymphosarcoma was diagnosed.
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Primary uterine non-Hodgkin lymphoma (NHL) is rarely reported, as its incidence is extremely low. We describe a 72 year old patient with primary uterine non-Hodgkin's lymphoma stage IV, diffuse B-cell large cells, who responded well to cytotoxic chemotherapy (R-CHOP). Radiological investigations exhibited certain characteristics, including magnetic resonance T2 weighted imaging, enhanced scanning, diffusion weighted imaging and apparent diffusion coefficient values.
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Article Synopsis
- Primary lymphoma of the female genital tract (PLFGT) is an uncommon type of lymphoma, with a study involving 60 women revealing that many cases were diagnosed around their early 50s.
- The uterus and ovaries were the most frequently affected sites, and diffuse large B-cell lymphoma (DLBCL) was the predominant subtype found in the majority of patients.
- The study indicated a median overall survival of approximately 13 years for DLBCL patients, with advanced disease stage correlating to a poorer prognosis, while CNS relapses were notably linked to patients with ovarian involvement who did not receive prophylactic treatment.
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