This unit covers statistical methods of linkage analysis that do not require the assumption of a detailed genetic model, as is required for standard lod score analysis. The unit has been updated to include the latest methods in sib-pair analysis, including updates to using the software program SIBPAL as well as the relative-pair analysis software applications GENEHUNTER, GENEHUNTER PLUS, and Merlin.
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http://dx.doi.org/10.1002/0471142905.hg0108s75 | DOI Listing |
Materials (Basel)
November 2024
Faculty of Mechanical Engineering, Fuel and Combustion Laboratory, University of Belgrade, Kraljice Marije 16, P.O. Box 35, 11120 Belgrade, Serbia.
Trends Hear
November 2024
Medizinische Physik and Cluster of Excellence Hearing4all, Universität Oldenburg, Oldenburg, Germany.
Inattention plays a critical role in the accuracy of threshold measurements, e.g., when using mobile devices.
View Article and Find Full Text PDFISA Trans
October 2024
Electrical & Electronics Engineering, Ege University, Izmir, Turkey. Electronic address:
Control of the family of systems that can be represented in the Euler Lagrange (EL) form is both challenging from a theoretical perspective and applicable to a broad spectrum of real systems. For this type of control problem, given that any parameter estimation error and disturbances are not directly addressed, the system performance deteriorates, and stability cannot be deduced in advance. Considering these issues, this work presents the design and the corresponding analysis of a saturation function based, model-free, continuous robust controller for mechanical systems represented in the EL form.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
October 2024
Department of Chemical Engineering, NIT Durgapur, 713209, Durgapur, West Bengal, India.
The pyrolysis characteristics of low-density polyethylene (LDPE) wastes were investigated in a batch pyrolyzer in the temperature range of 550-650 °C for a varying heating rate (5, 10, 15, 20, and 25 °C/min) alone and using kaolin catalyst (10, 15, and 20% w/w). The yield distribution of various products under varying operating conditions was investigated, and the corresponding favourable conditions for maximum yield of pyrolytic oil (PO) were identified. The possible effect of the catalyst on pyrolysis kinetics was explored by extracting activation energies from the TGA experiments.
View Article and Find Full Text PDFBMC Med
October 2024
Division of Urology, Department of Surgery, University of Cambridge, Cambridge, UK.
Background: The majority of men referred with a raised PSA for suspected prostate cancer will receive unnecessary tertiary investigations including MRI and biopsy. Here, we compared different types of biomarkers to refine tertiary referrals and when different definitions of clinically significant cancer were used.
Methods: Data and samples from 798 men referred for a raised PSA (≥ 3 ng/mL) and investigated through an MRI-guided biopsy pathway were accessed for this study.
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