Is HUB1 a hub for plant fitness?

Plant Signal Behav

Department of Plant Systems Biology, VIB, Gent, Belgium.

Published: December 2012

AI Article Synopsis

  • Researchers found that HUB1 influences circadian clock genes in Arabidopsis, impacting how these genes are expressed.
  • The hub1-1 mutant showed lower levels of histone H2B monoubiquitination at gene regions, leading to changes in circadian gene expression.
  • The study indicates that variations in histone modification via monoubiquitination can affect overall plant fitness in different HUB1 lines.

Article Abstract

Recently, we have identified circadian clock genes as targets of Histone Monoubiquitination1 (HUB1) in Arabidopsis from a transcriptome comparison between the hub1-1 mutant and HUB1 overexpression lines. HUB1 affected the amplitudes of the circadian clock gene expression profiles in the hub1-1 mutant that coincided with reduced monoubiquitination of histone H2B at their coding regions. Here we showed that parameters for plant fitness are altered in HUB1 mutant and overexpression lines, suggesting that the histone H2B monoubiquitination status affects plant fitness.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578887PMC
http://dx.doi.org/10.4161/psb.22326DOI Listing

Publication Analysis

Top Keywords

circadian clock
8
hub1-1 mutant
8
overexpression lines
8
histone h2b
8
plant fitness
8
hub1
5
hub1 hub
4
hub plant
4
plant fitness?
4
fitness? identified
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!