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Severe Cutaneous Manifestation of Malignant Syphilis in a Patient with Behçet's Uveitis: A Case Report.
Case Rep Ophthalmol
July 2024
Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Article Synopsis
- Syphilis can present in various ways, including ocular symptoms that may resemble Behçet's disease, highlighting the importance of distinguishing between the two conditions.
- A case involving a 38-year-old Thai man with Behçet's panuveitis developed complications from ocular syphilis despite initially negative tests, showcasing the complexity of diagnosis when immunomodulatory therapy is used.
- Treatment with intravenous penicillin G led to improvement, emphasizing the need for careful reevaluation and biopsy in cases where clinical presentations overlap.
Ulcerative erythematous papules and plaques on the face and lower legs of a man living with HIV: a clinicopathological challenge.
Int J Dermatol
November 2024
Department of Dermatology, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
Article Synopsis
- * His facial lesions appeared as violaceous plaques, while his lower legs displayed ulcerative lesions with necrosis and purple borders, resembling pyoderma gangrenosum and cutaneous lymphoma.
- * A biopsy and rapid plasma reagin test confirmed the diagnosis of lues maligna, leading to successful treatment with penicillin G benzathine.
An Exuberant Case of Ulceronodular-Rupioid (Malignant) Syphilis in an HIV Patient: A Proposal for New Diagnostic Criteria.
Infect Dis Rep
June 2024
Department of Medicine, Division of Infectious Diseases, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
We report the case of a 28-year-old male with uncontrolled human immunodeficiency virus (HIV) infection who presented with extensive ulcerated lesions with dark lamellated crusting on his face, torso, and limbs. The patient had a rapid plasma reagin (RPR) titer of 1:512, indicative of syphilis. A skin biopsy revealed granulomata surrounded by lymphocytes, histiocytes, and plasma cells, with spirochetes visible on immunohistochemical staining.
View Article and Find Full Text PDFLues maligna with neurosyphilis presenting in a diabetic, HIV-negative man.
Indian J Dermatol Venereol Leprol
May 2024
Department of Dermatology, The Second Affiliated Hospital, Xi'an Jiaotong University, Xincheng, Xi'an, China.
A case of secondary syphilis presenting like pemphigus with positive direct immunofluorescence.
JAAD Case Rep
December 2023
Department of Dermatology, University of Utah, Salt Lake City, Utah.
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