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Late-onset axial spondyloarthritis: data from Reuma-check cohort.
Clin Rheumatol
December 2024
Leiden University Medical Center, Leiden and Zuyderland Medical Center, Heerlen, The Netherlands.
Objectives: To estimate the prevalence of late-onset axial spondyloarthritis (lo-axSpA) and to identify clinical, laboratory, and imaging features associated with this phenotype.
Methods: This single-center, observational study included patients diagnosed with axSpA from the "Reuma-check" SpA program. Patients with a symptom onset ≥ 45 years were classified as lo-axSpA, as opposed to early-onset axSpA (eo-axSpA, onset < 45 years).
Real-world evidence on the benefits of optimal itch relief and skin clearance in atopic dermatitis management: a study from the TARGET-DERM AD registry.
J Dermatolog Treat
December 2024
Departments of Dermatology and Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
In atopic dermatitis (AD), the real-world impact of achieving itch and skin lesion treatment targets compared to partial improvement remains unclear. We assessed the relationship between itch relief (reduction in Worst Itch Numeric Rating Scale [WI-NRS]) and skin clearance (Investigator Global Assessment [IGA] 0/1) with other patient-reported outcomes. Using TARGET-DERM AD registry data on adults receiving standard-of-care treatment, we described and modeled the relationship of itch severity (Worst Itch Numeric Rating Scale [WI-NRS]) and skin lesion severity (IGA) outcomes with patient-reported (quality of life ([DLQI)], AD severity [(POEM]), sleep ([Sleep-NRS]), and skin pain [(Pain-NRS]).
View Article and Find Full Text PDFStudy of Subcutaneous Pressure in Lower Limb Cellulitis and its Correlation With Surgical Intervention.
Cureus
November 2024
Department of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.
Introduction Cellulitis is a prevalent bacterial skin infection, particularly affecting the lower limbs and often necessitating clinical intervention due to its considerable incidence rate. Factors like venous insufficiency, lymphedema, and recurring episodes increase the risk of relapse, complicating treatment strategies. Although antibiotics and limb elevation are standard care, severe cases may require surgical intervention.
View Article and Find Full Text PDFSustained Aesthetic Improvement in Midface Micro-Autologous Fat Transplantation Auxiliary Support on Lower Eyelid Rejuvenation: A Comprehensive Evaluation.
Aesthetic Plast Surg
December 2024
Department of Plastic Surgery, Jiangsu Province Hospital of Chinese Medicine, Nanjing, 210001, Jiangsu Province, China.
Purpose: To evaluate the deformities of tear troughs, and contours of the infraorbital-midfacial region, and to observe the clinical therapeutic effects of lower eyelid reconstruction combined with micro-autologous fat transplantation in orbital-midfacial rejuvenation.
Methods: A total of 87 individuals seeking cosmetic improvement, aged 25 to 45 years (mean age 36.7 years), were selected for this study from March 2020 to March 2022.
Incidence and prevalence of prurigo nodularis and associated comorbidities in Denmark from 1995 to 2021.
Clin Exp Dermatol
November 2024
Medical Affairs, Sanofi A/S, Denmark.
Introduction: Prurigo nodularis (PN) is a chronic skin condition characterized by intense itching from nodular skin lesions. Despite its impact on patients' quality of life, limited data exist on its epidemiology.
Methods: A national register-based study in Denmark was conducted, utilizing data from Danish national health registers to determine the incidence and prevalence of PN diagnosed in hospitals from 1995 to 2021 and to explore the occurrence of comorbidities.
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