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Similar Publications

Amiodarone-Induced Anaphylaxis.

J Pharm Pract

February 2025

Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Ivins, UT, USA.

Amiodarone-induced anaphylaxis is seldom reported. The mechanism of this anaphylaxis is unknown. A literature search was carried out with keywords "Amiodarone" and "Anaphylaxis" and "polysorbate 80" or "hypotension.

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Amiodarone is a commonly used antiarrhythmic used to treat atrial fibrillation and ventricular tachycardias. While this agent can present with pulmonary, thyroid, and hepatic side effects, it can also, less commonly cause neurologic toxicity, particularly optic neuropathy. Optic neuropathy can manifest as acute vision loss.

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Amiodarone-Induced Hyponatremia in An Elderly Patient: A Rare Case Report.

J Pharm Pract

June 2023

Department of Geriatric Medicine, JSS Medical College & Hospital, JSS Academy of Higher Education and Research, Mysore, India.

Article Synopsis
  • - Amiodarone is a Class III antiarrhythmic drug that can have serious side effects, leading to therapy discontinuation in around 20% of patients due to issues like liver damage and thyroid dysfunction.
  • - A case study highlighted a 73-year-old woman with severe hyponatremia linked to her amiodarone treatment for hypertension and ischemic heart disease, resulting in multiple hospital visits.
  • - The report emphasizes the need for healthcare providers to consider hyponatremia as a potential side effect of amiodarone, as it is not widely recognized in existing literature.
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Giant cell arteritis (GCA) is a common medium to large vessel vasculitis of the elderly that can lead to permanent vision loss. Neuroimaging in GCA may reveal optic nerve sheath enhancement, which is a cardinal finding of optic perineuritis (OPN). The clinical manifestations of GCA can mimic that of other ocular disorders including amiodarone-associated optic neuropathy (AAON).

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Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic.

Rev Cardiovasc Med

March 2021

Department of Cardiology, Epworth Healthcare, Melbourne, 3121 Victoria, Australia.

Amiodarone is a common antiarrhythmic drug that is utilised in clinical practice and is associated with pulmonary toxicity. The most common form of pulmonary complication is interstitial pneumonitis which is treated with discontinuation of amiodarone and initiation of corticosteroids. Amiodarone-induced pulmonary eosinophilia is a rare complication of amiodarone therapy, with blood and pulmonary eosinophilia the predominant features.

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