Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490703PMC
http://dx.doi.org/10.1039/c2an35877hDOI Listing

Publication Analysis

Top Keywords

breast cancer
12
cancer cells
12
fluorescent polymer-based
4
polymer-based post-translational
4
post-translational differentiation
4
differentiation subtyping
4
subtyping breast
4
cells report
4
report application
4
application synthesized
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!