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Objectives: To understand the competitive position of the UK in comparison to Europe and the USA for haematological cancer clinical research.
Design: Using commercially available databases, clinical trial numbers, their effectiveness and publication outputs were evaluated in two analyses: a macrodevelopment and a research activity and performance analysis.
Data Sources: The following databases were used for this analysis: Organisation for Economic Co-operation and Development, Thomson Reuters Incidence and Prevalence, the Cortellis Clinical Trial Intelligence, the Clarivate Cortellis Innography Patent Intelligence, Thomson-Reuters Cortellis Regulatory Intelligence, Thomson Reuters Web of Science and data from the Centre for Medicine Research (CMR).
Improving surgical quality of care: learning from 8,331 surgical medical malpractice cases.
Front Med (Lausanne)
December 2024
School of Nursing, Southwest Medical University, Luzhou, China.
Objective: This study aimed to analyze the characteristics of surgical litigation cases and the risk factors that contribute to catastrophic compensation.
Methods: We downloaded and retrieved all cases related to surgical litigation cases from the China Jufaanli Database between 2008 and 2023. Multivariate logistic regression analysis was employed to identify independent risk factors that may contribute to catastrophic compensation.
Medical malpractice court cases involving treatment of the temporomandibular joint: analysis of prevalence, risk factors, and court rulings.
Oral Surg Oral Med Oral Pathol Oral Radiol
October 2024
Department of Oral and Maxillofacial Surgery, Harvard School of Dental Medicine, Boston, MA, USA.
Article Synopsis
- Limited research has examined malpractice in dentistry, particularly related to temporomandibular joint disorders (TMDs), which are treated by various dental specialists.
- A study reviewed malpractice court cases from 1960 to 2022, identifying 57 relevant cases that met specific criteria for inclusion.
- The results showed that 81% of cases were ruled in favor of the healthcare provider, often due to the expiration of the statute of limitations, indicating that healthcare actions were generally considered appropriate within the standard of care.
Revealing novel CD8 T-cell epitopes from the H5N1 avian influenza virus in HBW/B1 haplotype ducks.
Vet Res
December 2024
National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control, Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
The duck CD8 T-cell response effectively defends against H5N1 highly pathogenic avian influenza virus (HPAIV) infection, but the recognized peptide is rarely identified. Here, we found that the ratio of CD8 T cells and the expression of IFN-γ and cytotoxicity-associated genes, including granzyme A/K, perforin and IL2, at 7 days post-infection in peripheral blood mononuclear cells (PBMCs) from B1 haplotype ducks significantly increased in the context of defending against H5N1 AIV infection in vivo. Moreover, similar results were observed in cultured and sorted H5N1 AIV-stimulated duck CD8 T cells in vitro.
View Article and Find Full Text PDFLitigation Following Surgery for Acute Traumatic Facial Injuries.
Cureus
October 2024
Otolaryngology - Head and Neck Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Introduction: The knowledge of malpractice claims after surgery for acute traumatic facial injuries can inform surgeons about potential litigation risks, case complications, and reasons for patient dissatisfaction.
Methods: The Westlaw Campus Research and LexisNexis legal databases were searched for all available court decisions associated with cases brought to suit following surgery for traumatic facial injuries. The plaintiff characteristics, date, location, specialty of the defendant, allegations, and adjudicated case outcomes were obtained from case documents and analyzed.
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