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YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database.
BMC Biol
January 2025
Institute of Rare Diseases, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610000, Sichuan, China.
Background: The advancements in second-/third-generation sequencing technologies, alongside computational innovations, have significantly enhanced our understanding of the genomic structure of Y-chromosomes and their unique phylogenetic characteristics. These researches, despite the challenges posed by the lack of population-scale genomic databases, have the potential to revolutionize our approach to high-resolution, population-specific Y-chromosome panels and databases for anthropological and forensic applications.
Objectives: This study aimed to develop the highest-resolution Y-targeted sequencing panel, utilizing time-stamped, core phylogenetic informative mutations identified from high-coverage sequences in the YanHuang cohort.
Racial/ethnic differences in post-acute sequelae of SARS-CoV-2 in children and adolescents in the United States.
Nat Commun
January 2025
The Center for Health AI and Synthesis of Evidence (CHASE), University of Pennsylvania, Philadelphia, PA, USA.
Racial/ethnic differences are associated with the symptoms and conditions of post-acute sequelae SARS-CoV-2 infection (PASC) in adults. These differences may exist among children and warrant further exploration. We conducted a retrospective cohort study with difference-in-differences analyzes to assess these differences in children and adolescents under the age of 21.
View Article and Find Full Text PDFIncidence, long-term predictors and progression of chronic kidney disease among African migrants and non-migrants: the transcontinental population-based prospective RODAM cohort study.
BMJ Glob Health
January 2025
Public and Occupational Health, University of Amsterdam, Amsterdam, The Netherlands.
Background: Limited longitudinal data exist on chronic kidney disease (CKD) in African populations undergoing epidemiological transitions. We investigated incidence, long-term predictors and progression of CKD among Ghanaians residing in Ghana and Ghanaian migrants in the Netherlands (Amsterdam).
Methods And Findings: We analysed data from 2183 participants in the transcontinental population-based prospective Research on Obesity and Diabetes among African Migrants cohort, followed for approximately 7 years.
Association of sarcopenia with Parkinson's disease and related functional degeneration among older adults: A prospective cohort study in Europe.
J Affect Disord
January 2025
Department of Global Health, School of Public Health, Peking University, Beijing 100191, China. Electronic address:
Background: Former evidence on the risk factors for Parkinson's disease (PD), especially the PD-related functional limitation and neurological outcomes was scarce. We aimed to explore the association between sarcopenia and PD along with the PD-related functional degeneration. Further, we testified the heterogeneity in the above relationships of multimorbidity severity and patterns.
View Article and Find Full Text PDFUsing a STEM Course on Inclusion, Diversity, Equity, and Accessibility to Explore Student Reflections on their Socialization into STEM and their Observations of the Figured World of Higher Education STEM Contexts.
CBE Life Sci Educ
March 2025
Center for Teaching and Learning Excellence, Syracuse University, Syracuse, NY 13210.
Science remains an exclusionary field to people who do not align with "acceptable" worldviews (e.g., white, Western, masculine).
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