AI Article Synopsis
- The text discusses a straightforward method for creating a specific type of amino acid called an azepane quaternary amino acid in a pure form.
- Research involving theoretical models, NMR, and X-ray studies reveals that this amino acid can effectively stabilize 3(10) helical structures found in short peptides.
- This finding may have implications for understanding protein structures and developing new materials in biochemistry.
Article Abstract
A simple method for the synthesis of an azepane quaternary amino acid in enantiopure form is described. Theoretical, NMR, and X-ray studies indicated that this azepane-derived amino acid is an effective stabilizer of 3(10) helical structures in short peptides.
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| http://dx.doi.org/10.1021/jo301379r | DOI Listing |
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