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Purple Tea (Camellia sinensis var. assamica) Leaves and Obesity Management: A Review of 1,2-Di-Galloyl-4,6-Hexahydroxydiphenoyl-β-D-Glucose's (GHG) Potential Health Benefits, and Future Prospects.
Cureus
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Pharmaceutical Biotechnology and Microbiology, Vidya Herbs USA, Bunnell, USA.
Purple tea ( var. ) is a distinct variety of known for its bioactive compounds, including caffeine, catechins, and a unique compound called 1,2-di-Galloyl-4,6-Hexahydroxydiphenoyl-β-D-Glucose, (GHG) found predominantly in purple tea leaves, which shows potential in obesity management. Studies have indicated that these bioactive compounds play a significant role in reducing BMI and body weight among obese patients.
View Article and Find Full Text PDF[Effects of muscle fatigue on urine metabolites in automobile manufacturing workers based on untargeted metabolomics].
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December 2024
Laboratory of Occupational Protection and Ergonomics Research, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
To investigate the changes of metabolites in urine of automobile manufacturing workers with muscle fatigue using metabolomics technology, and to explore potential biomarkers and disrupted metabolic pathways. In July 2022, urine samples were collected from 35 male workers in a certain automobile manufacturing industry before and after muscle fatigue, and metabolite analysis was conducted. Subsequently, multivariate statistical analysis was used for data processing to screen differential metabolites.
View Article and Find Full Text PDFThe Neuroprotective Effects of Caffeine in a Neonatal Hypoxia-Ischemia Model are Regulated through the AMPK/mTOR Pathway.
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Department of Neonatology and Pediatric Intensive Care, Children's Hospital University of Bonn, Bonn, Germany.
Article Synopsis
- Neonatal hypoxic-ischemic encephalopathy (HIE) is a leading cause of death and disability in newborns, and caffeine has shown promise in mitigating its effects.
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Preclinical Evidence for a Drug-Drug Interaction Between Cannabinol and Melatonin.
Basic Clin Pharmacol Toxicol
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Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
The worldwide legalization of medicinal cannabis has led to an increased use of products made by commercial operators. These products often contain minor cannabinoids such as cannabinol (CBN) which are advertised to improve sleep. Products are also available in which CBN is combined with conventional therapies, with a common product containing both CBN and the widely used sleep-aid melatonin.
View Article and Find Full Text PDFInhibition of Oral Biofilms and Enhancement of Anticancer Activity on Oral Squamous Carcinoma Cells Using Caffeine-Coated Titanium Oxide Nanoparticles.
Chem Biodivers
December 2024
Saveetha University - Poonamallee Campus: SIMATS Deemed University, Biochemistry, Ponnamallee, 600077, Chennai, INDIA.
The fungus Candida albicans is a prominent cariogenic fungal agent that works in association with Streptococcus mutans to accelerate the formation of oral cancer and tooth decay. This study evaluates caffeine-encapsulated titanium oxide nanoparticles (CF-TiO2 NPs) for their potential to prevent biofilm formation on teeth and enhance oral anticancer treatment by influencing apoptotic gene regulation. The synthesized CF-TiO2 NPs were characterized using UV, SEM, EDAX, and FTIR analyses, and their antioxidant activity was confirmed through free radical quenching studies.
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