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Correlation between 25-hydroxyvitamin D level of lactating mothers and bone mineral density of infants and analysis of risk factors.
J Med Biochem
November 2024
Maternal and Child Health Hospital of Hubei Province, Department of Child Health, Wuhan, Hubei Province, China.
Background: Aim was to demonstrate the influencing factors of infant bone mineral density (BMD) and its correlation with serum 25-hydroxyvitamin D (25-(OH)D) in nursing mothers.
Methods: 200 children aged 0 č 1 years were rolled into normal group (n=120) and abnormal group (n=80) regarding the results of ultrasound BMD examination. The sunshine duration of infants with different BMD and 25(OH)D, calcium and phosphorus levels of nursing mothers were analyzed, and univariate and multivariate analyses of BMD were implemented.
Does pregnancy in adolescence increase the chances of osteoporosis among aged women? Findings from the ELSI study.
Australas J Ageing
March 2025
Faculty of Nutrition, Federal University of Alfenas, Alfenas, Minas Gerais, Brazil.
Objective: Bone mineral density changes during the life span, rising rapidly during adolescence, plateauing around 30 years of age and decreasing in later years. Life events such as pregnancy and lactation temporarily reduce bone density, and their long-term effects on osteoporosis development are still unclear. This study aimed to analyse the association between pregnancy in adolescence and osteoporosis in aged women.
View Article and Find Full Text PDFEffects of low phosphorus diets on phosphorus balance and plasma concentrations of 25-hydroxyvitamin D3, and carboxy-terminal collagen crosslinks during the transition period in dairy cows.
J Dairy Sci
January 2025
Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, the Netherlands.
Our aim was to determine the effects of P intake on P balance, serum parathyroid hormone (PTH) levels and bone resorption during the final 4 weeks prepartum and the first 8 weeks of lactation. Sixty pregnant multiparous Holstein Friesian dairy cows were assigned to a randomized block design with repeated measurements and dietary treatments arranged according to a 2 × 2 factorial design. The experimental diets contained 3.
View Article and Find Full Text PDFEffect of romosozumab on bone mineral density and trabecular bone score in premenopausal women with low bone mass.
Osteoporos Int
January 2025
Department of Internal Medicine, Severance Hospital, Endocrine Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Unlabelled: We investigated the efficacy of romosozumab in premenopausal women with low bone mass. Romosozumab substantially increased bone mineral density and trabecular bone score in these women, aligning with its proven therapeutic benefits for postmenopausal osteoporosis.
Purpose: Romosozumab, an anti-sclerostin antibody, is a promising anabolic agent that increases bone formation and decreases bone resorption.
Effect of 25-hydroxycholecalciferol and high phytase doses on performance, vitamin D status, bone mineralization, and mechanistic target of rapamycin gene expression of broilers.
Animal
October 2024
Department of Animal Science, Federal University of Paraná, Curitiba, PR 80035-050, Brazil.
The use of exogenous phytase and vitamin D metabolites such as 25-hydroxycholecalciferol (25-OH-D) for poultry is well consolidated, but the potential for additive effects when supplementing both requires further investigation. This study investigated possible interactions between supplementation of 25-OH-D and high doses of phytase for broilers fed Ca- and P-deficient diets. A total of 1 200 one-d-old male broiler chicks were randomly allocated from one of four dietary treatments in a 2 × 2 factorial arrangement: 600 or 2 000 phytase units (FYT)/kg and with or without the inclusion of 25-OH-D at 69 µg/kg, with 12 replicates of 25 broilers each.
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