Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing.

J Clin Microbiol

Department of Nutrition and Food Science and Joint Institute for Food Safety and Applied Nutrition, University of Maryland, College Park, Maryland, USA.

Published: December 2012

Non-O157 Shiga toxin-producing Escherichia coli (STEC) strains are emerging food-borne pathogens causing life-threatening diseases and food-borne outbreaks. A better understanding of their evolution provides a framework for developing tools to control food safety. We obtained 15 genomes of non-O157 STEC strains, including O26, O111, and O103 strains. Phylogenetic trees revealed a close relationship between O26:H11 and O111:H11 and a scattered distribution of O111. We hypothesize that STEC serotypes with the same H antigens might share common ancestors.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502965PMC
http://dx.doi.org/10.1128/JCM.02262-12DOI Listing

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