Sulfate-reducing bacteria reveal a new branch of tetrapyrrole metabolism.

Adv Microb Physiol

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República EAN, Oeiras, Portugal.

Published: March 2013

Sulfate-reducing microorganisms are a diverse group of bacteria and archaea that occupy important environmental niches and have potential for significant biotechnological impact. Desulfovibrio, the most studied genus among the sulfate-reducing microorganisms, contains proteins with a wide variety of tetrapyrrole-derived cofactors, including some unique derivatives such as uroporphyrin I and coproporphyrin III. Herein, we review tetrapyrrole metabolism in Desulfovibrio spp., including the production of sirohaem and cobalamin, and compare and contrast the biochemical properties of the enzymes involved in these biosynthetic pathways. Furthermore, we describe a novel pathway used by Desulfovibrio to synthesize haem b, which provides a previously unrecognized link between haem, sirohaem, and haem d(1). Finally, the organization and regulation of genes involved in the tetrapyrrole biosynthetic pathway is discussed.

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-394423-8.00007-XDOI Listing

Publication Analysis

Top Keywords

tetrapyrrole metabolism
8
sulfate-reducing microorganisms
8
sulfate-reducing bacteria
4
bacteria reveal
4
reveal branch
4
branch tetrapyrrole
4
metabolism sulfate-reducing
4
microorganisms diverse
4
diverse group
4
group bacteria
4

Similar Publications

Significance: Protoporphyrin IX (PpIX) delayed fluorescence (DF) is inversely related to the oxygen present in tissues and has potential as a novel biomarker for surgical guidance and real-time tissue metabolism assessment. Despite the unique promise of this technique, its successful clinical translation is limited by the low intensity emitted.

Aim: We developed a systematic study of ways to increase the PpIX DF signal through acquisition sampling changes, allowing optimized imaging at video rates.

View Article and Find Full Text PDF

Cotton is essential for the global textile industry however, climate change, especially extreme temperatures, threatens sustainable cotton production. This research aims to identify breeding strategies to improve heat tolerance and utilize stress-resistant traits in cotton cultivars. This study investigated heat tolerance for 50 cotton genotypes at the seedling stage by examining various traits at three temperatures (32 °C, 45 °C and 48 °C) in a randomized plot experiment.

View Article and Find Full Text PDF

Three-dimensional diffractive acoustic tomography.

Nat Commun

January 2025

Department of Biomedical Engineering, Duke University, Durham, NC, USA.

Acoustically probing biological tissues with light or sound, photoacoustic and ultrasound imaging can provide anatomical, functional, and/or molecular information at depths far beyond the optical diffusion limit. However, most photoacoustic and ultrasound imaging systems rely on linear-array transducers with elevational focusing and are limited to two-dimensional imaging with anisotropic resolutions. Here, we present three-dimensional diffractive acoustic tomography (3D-DAT), which uses an off-the-shelf linear-array transducer with single-slit acoustic diffraction.

View Article and Find Full Text PDF

Wheat (Triticum aestivum L.) productivity and quality can be threatened by soil cadmium (Cd) contamination, posing a concern to food security. Salicylic acid (SA) is an endogenously produced signaling molecule that activates the defense system imparting abiotic stress tolerance in plants.

View Article and Find Full Text PDF

Associations between serum total bilirubin and overactive bladder from the National Health and Nutrition Examination Survey.

Front Endocrinol (Lausanne)

January 2025

Department of Urology, Affiliated Yancheng Hospital, School of Medicine, Southeast University, Yancheng, Jiangsu, China.

Background: The relationship between serum total bilirubin (STB) concentrations and the risk of overactive bladder (OAB) remains uncertain. This study aims to explore the potential connection between STB and OAB.

Method: We utilized data from the National Health and Nutrition Examination Survey (NHANES) database for the years 2001-2020.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!