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Med Image Comput Comput Assist Interv
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Memorial Sloan Kettering Cancer Center, New York, USA.
Histology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical workflows). However, the cumulative costs of digital multi-slide high-speed brightfield scanners, cloud/on-premises storage, and personnel (IT and technicians) make the current slide digitization workflows out-of-reach for limited-resource settings, further widening the health equity gap; even single-slide manual scanning commercial solutions are costly due to hardware requirements (high-resolution cameras, high-spec PC/workstation, and support for only high-end microscopes). In this work, we present a new cloud slide digitization workflow for creating scanner-quality whole-slide images (WSIs) from uploaded low-quality videos, acquired from cheap and inexpensive microscopes with built-in cameras.
View Article and Find Full Text PDFDuodenal Leishmaniasis Mimicking Celiac Disease in HIV Patient: A Case Report and Literature Review.
Cureus
May 2024
Gastrointestinal Endoscopy, Hospital das Clínicas de Ribeirão Preto, Ribeirão Preto, BRA.
It is known that there are several clinical forms that diseases can take when presented in patients living with HIV, especially those in the AIDS phase. Here, we present a case that demonstrates the peculiar capacity of diseases to assume the most varied forms, highlighting the limited research on neglected infectious parasitic diseases. This study aimed to underscore the ability of these diseases to mimic other pathologies, emphasizing the importance of infectious diseases as differential diagnoses in the most diverse clinical entities, as is the case of visceral leishmaniasis.
View Article and Find Full Text PDFHistological and neuronal changes in the duodenum of hamsters infected with Leishmania (Leishmania) infantum.
Exp Parasitol
August 2022
Animal Morphophysiology Laboratory, Department of Biological and Environmental Sciences, São Paulo State University (UNESP), São Vicente, 11.380-97, Brazil. Electronic address:
Visceral leishmaniasis is a neglected tropical disease caused by parasites belonging to the Leishmania genus that infect macrophages in different tissues such as the spleen, liver, lymph nodes, bone marrow, and intestine. Therefore, this study aimed to investigate the integrity of the intestinal tract and the nitrergic (NADPH-dp) and metabolically active (NADH-dp) myenteric neurons of the duodenum of golden hamsters infected with L. (L.
View Article and Find Full Text PDFTopical sucralfate for treatment of mucocutaneous conditions: A systematic review on clinical evidences.
Dermatol Ther
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School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Sucralfate is an aluminum salt of sucrose octasulfate, generally considered safe in terms of adverse effects. Systemic sucralfate is FDA-approved for the treatment of duodenal ulcers. Since 1991, topical sucralfate has been used in various mucocutaneous conditions, but it is not approved by the FDA yet.
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Exp Clin Transplant
March 2022
From the Department of Nephrology and Renal Transplant Medicine, Medanta, The Medicity, Gurugram, India.
Infection caused by Leishmania species has been increasingly reported in solid-organ transplant recipients since the first case report in 1979. Visceral leishmaniasis is endemic in central and eastern regions of India. Clinical features may simulate a variety of other infections, and a high index of suspicion is required for the diagnosis.
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