Objective: Far-out syndrome (FOS) is a rare incident caused by L5 nerve root entrapment in the far-out area, the L5-S1 extraforaminal area between the transverse process and the sacral ala. The purpose of this study is to disclose the middle-term surgical outcomes of microscopic posterior decompression in the far-out area (MPDFA).
Material And Methods: From June 2008 to November 2010, eight patients with FOS (six men and two women, mean age 65.4 years) were treated with MPDFA. Their chief complaint was leg pain in the L5 nerve root distribution area. Nerve root impingements in the far-out area were confirmed by magnetic resonance imaging, computed tomography and selective radiculography. Indications for MPDFA were given when pain was uncontrollable with conservative treatments for more than 1 month. MPDFA was performed according to the following procedure: a 4-to-5-cm skin incision was made just above the far-out area. The far-out area was exposed using Wiltse's intermuscular approach. The nerve root was decompressed with partial resection of the transverse process and the sacral ala, and removal of the iliolumbar ligament. Surgical outcomes were evaluated at periodical examinations with the Japanese Orthopedic Score (JOA) and a Visual Analogue Scale (VAS) of the leg pain. The mean follow-up period was 24.3 months (ranging from 12 to 40 months).
Results: All patients had reduced radicular leg pain after their operations. The mean postoperative hospital stay was 11.4 days, and the patients returned to their normal activities of daily living immediately after discharge. Both JOA and the VAS scores improved after surgery. The scores temporarily worsened in two patients with degenerative scoliosis; the worsening was attributed not to recurrence of the radiculopathy but to pain arising from knee arthropathy. The scores were maintained in the other patients at least until the final examinations during the follow-up.
Conclusion: MPDFA is a less-invasive surgery for treating FOS and can provide a good middle-term surgical outcome.
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http://dx.doi.org/10.1055/s-0032-1327443 | DOI Listing |
J Clin Microbiol
August 2022
Laboratory of Viruses, Microbiology Department, Biological Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Prior studies have demonstrated prolonged presence of yellow fever virus (YFV) RNA in saliva and urine as an alternative to serum. To investigate the presence of YFV RNA in urine, we used RT-PCR for YFV screening in 60 urine samples collected from a large cohort of naturally infected yellow fever (YF) patients during acute and convalescent phases of YF infection from recent YF outbreaks in Brazil (2017 to 2018). Fifteen urine samples from acute phase infection (up to 15 days post-symptom onset) and four urine samples from convalescent phase infection (up to 69 days post-symptom onset), were YFV PCR-positive.
View Article and Find Full Text PDFActa Neurochir (Wien)
October 2021
Neurosurgery, Endoscopic Spine Surgery Center, Seoul Bumin Hospital, 389, Gonghang-daero, Gangseo-gu, 7590, Seoul, South Korea.
Background: The development of specialized instruments and surgical techniques has enabled the biportal endoscopic system to access the foraminal and extraforaminal area using the contralateral sublaminar approach at the lumbar level.
Methods: Biportal endoscopic contralateral sublaminar approach was used to resolve the contralateral foraminal, and extraforaminal stenosis at the lumbar level. Prominent syndesmophytes and herniated disc compression of the exiting nerve root were successfully removed, and the distorted nerve root was restored to a smooth downward angulation in the far-out area.
Arch Iran Med
May 2021
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: In developing countries like Iran, the burden of obesity increases through comorbid diseases. We estimated the mean body mass index (BMI) and prevalence of overweight/obesity by components of sex, age, province, and year in Iran from 1990 to 2016.
Methods: Through a comprehensive systematic review, all relevant data sources pooled results with individual level national and sub-national population-based studies.
JBI Evid Synth
June 2021
Memorial University Faculty of Nursing Collaboration for Evidence-Based Nursing and Primary Health Care: A JBI Affiliated Group, St. John's, NL, Canada.
Objective: The objective of this review was to synthesize the literature on the experiences of older adults accessing specialized health care services while living in remote or rural areas.
Introduction: Older persons with chronic illnesses often need specialized health care services. Those who live in remote or rural areas may have limited access to these specialized health care services, potentially leading to an increase in morbidity and mortality.
Eur Heart J
June 2021
Department of Medicine, University of Mississippi Medical Center, 2500 North State St, Jackson, MS, 39216, USA.
Globally, there has been little change in mortality rates from cardiovascular (CV) diseases or cancers over the past two decades (1997-2018). This is especially true for heart failure (HF) where 5-year mortality rates remain as high as 45-55%. In the same timeframe, the proportion of drug revenue, and regulatory drug approvals for cancer drugs, far out paces those for CV drugs.
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