Distinctive metabolism associated with particular cell states is increasingly being defined in normal and malignant cells. Ito et al. (2012) now show that fatty acid oxidation is associated with hematopoietic stem cells and determines whether they undergo symmetric or asymmetric cell division, driving a fundamental property of the stem cell state.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045100 | PMC |
| http://dx.doi.org/10.1016/j.cmet.2012.09.011 | DOI Listing |
Publication Analysis
Top Keywords
stem cell
8
cell division
8
fate fat
4
fat lipid
4
lipid metabolism
4
metabolism determines
4
determines stem
4
cell
4
division outcome
4
outcome distinctive
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!