Scientists in the various fields of aging share a common goal--the extension of healthy life. However, claiming that the only way to accomplish this is to treat the complications of aging rather than its causes requires more than declarations made by proponents of SENS--it requires empirical research based on the scientific method. As this paper illustrates, it will be difficult to prove that SENS interventions work because the primary result of interest, negligible senescence, is not an outcome variable in empirical tests of SENS.
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http://dx.doi.org/10.1159/000342959 | DOI Listing |
Front Parasitol
August 2024
Veterinary Health Innovation Engine, University of Surrey, Guildford, United Kingdom.
species are parasitic organisms of vertebrates with a worldwide distribution. They have an important impact globally upon human and animal health, and livestock productivity. The life cycle of these species is complex and difficult to disrupt to improve human health, animal health, food security and economic growth.
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January 2025
Fisheries Research Station Baden-Württemberg, Argenweg 50/1, 88085 Langenargen, Germany.
Adaptive divergence and increased genetic differentiation among populations can lead to reproductive isolation. In Lake Constance, Germany, a population of invasive three-spined stickleback () is currently diverging into littoral and pelagic ecotypes, which both nest in the littoral zone. We hypothesized that assortative mating behaviour contributes to reproductive isolation between these ecotypes and performed a behavioural experiment in which females could choose between two nest-guarding males.
View Article and Find Full Text PDFPhilos Trans A Math Phys Eng Sci
January 2025
Indian Institute of Technology Gandhinagar, Gandhinagar, Gujarat, India.
Modern language models such as bidirectional encoder representations from transformers have revolutionized natural language processing (NLP) tasks but are computationally intensive, limiting their deployment on edge devices. This paper presents an energy-efficient accelerator design tailored for encoder-based language models, enabling their integration into mobile and edge computing environments. A data-flow-aware hardware accelerator design for language models inspired by Simba, makes use of approximate fixed-point POSIT-based multipliers and uses high bandwidth memory (HBM) in achieving significant improvements in computational efficiency, power consumption, area and latency compared to the hardware-realized scalable accelerator Simba.
View Article and Find Full Text PDFMicrob Cell Fact
January 2025
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Background: Aspergillus niger is an important industrial filamentous fungus used to produce organic acids and enzymes. A wide dynamic range of promoters, particularly strong promoters, are required for fine-tuning the regulation of gene expression to balance metabolic flux and achieve the high yields of desired products. However, the limited understanding of promoter architectures and activities restricts the efficient transcription regulation of targets in strain engineering in A.
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January 2025
School of Life and Health Sciences & College of Tropical Crops, Hainan University, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
Background: Banana Fusarium wilt caused by Fusarium oxysporum f. sp. cubense is a soil-borne fungal disease.
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