In this paper, we investigate the effect of non-uniformities (enlargement of current passage, non-equal surface current densities, etc.) in axial as well as transverse directions of a porous silicon Fabry-Perot (FP) cavity as well as loss nature of bulk silicon on spectral properties of this cavity, even that cavity is created with an anisotropic etching process. Without correct and comprehensive characterization of such cavities by incorporating these non-uniformities and inherent lossy nature of a cavity, detection and identification of biological and chemical molecules by that cavity may yield unpredictable and misleading results. From our simulations, we note the following two key points. First, effects of the refractive index and the thickness of microcavity region of a lossless or lossy FP cavity on resonance wavelength is more prevailing than those of first and last layers. Second, the effect of some small loss inside the FP cavity is not detectable by the measurement of resonance wavelength whereas the same influence is noticeable by the measurement of reflectivity. We carried out some measurements from two different regions on the fabricated cavities to validate our simulation results. From a practical point of view in correct detection and/or identification of lossy biological or chemical vapor by FP cavities, we conclude that not only the measurement of resonance wavelength as well as its shift but also the reflectivity value at the resonance wavelength or some specific wavelengths should be utilized.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/OE.20.022208 | DOI Listing |
Anal Chem
January 2025
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, College of Energy, Discipline of Intelligent Instrument and Equipment, Cancer Center and Department of Breast and Thyroid Surgery, Department of Ultrasound, Xiang'an Hospital of Xiamen University, School of Medicine, Laboratory Animal Center Xiamen University, Xiamen University, Xiamen 361005, China.
With the increasing incidence of thyroid cancer worldwide and the increasing demand for surgery, the risk of parathyroid injury is also increasing, which will lead to postoperative hypoparathyroidism (HP) and hypocalcemia. In order to improve the quality of life of patients after surgery, there is an urgent need to develop a novel platform that can identify the parathyroid gland immediately during surgery. The parathyroid gland promotes the increase of blood calcium concentration by secreting parathyroid hormone (PTH).
View Article and Find Full Text PDFAnal Chim Acta
March 2025
Artificial Intelligence Research Center, Chang Gung University, Taoyuan, 333323, Taiwan; Department of Artificial Intelligence, College of Intelligent Computing, Chang Gung University, Taoyuan, 333323, Taiwan. Electronic address:
Background: In recent years, employing deep learning methods in the biosensing area has significantly reduced data analysis time and enhanced data interpretation and prediction accuracy. In some SPR fields, research teams have further enhanced detection capabilities using deep learning techniques. However, the application of deep learning to spectroscopic surface plasmon resonance (SPR) biosensors has not been reported.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Chemistry, College of Science, Rikkyo University, 3-34-1, Nishi-Ikebukuro, Toshima, Tokyo 171-8501, Japan. Electronic address:
A novel aluminum (Al)-based surface plasmon resonance (SPR) sensor operating in the far-ultraviolet (FUV, <200 nm) region has been developed. By utilizing a thinner Al film compared to previously reported deep-ultraviolet (DUV, <300 nm) SPR sensors, the SPR wavelength was effectively maintained within the FUV region across various liquids. In the presence of resonant molecules, the SPR wavelength shift was notably enhanced.
View Article and Find Full Text PDFWave mixing (WM) techniques are crucial for applications such as supercontinuum generation, frequency conversion, and high-dimensional quantum encoding. However, their efficiency is often limited by complex phase-matching requirements, and current insights into phase-matching mechanisms for high-order WM remain limited. To address this, compact optical path configurations with high-peak-power, synchronous, multicolor ultrafast laser sources are needed to enhance high-order wave-mixing efficiency.
View Article and Find Full Text PDFAdvancements in plasmonic sensing require simultaneous detection capability that ensures large-scale detection with reduced losses. In this work, we propose a new solid-core fiber-based refractive index (RI) sensor with an ultra-broad detection range. The proposed fiber consists of a relatively simple single-ring cladding with six circular tubes in which the light is guided in the core based on the inhibited-coupling (IC) mechanism.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!