A new cyclic tetrapeptide (1), along with known congeners (2, 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai. The absolute configuration of 1 was determined using the modified Mosher's method and Marfey's method. Compound 1 displayed a weak suppressive effect on the production of nitric oxide (NO) in murine macrophage cells (RAW264.7) without notable cytotoxicity.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
cyclic tetrapeptide
8
fungus phoma
8
tetrapeptide jellyfish-derived
4
jellyfish-derived fungus
4
phoma cyclic
4
tetrapeptide congeners
4
congeners isolated
4
isolated fungus
4
phoma derived
4
derived giant
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!