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Nasal effects of environmental tobacco smoke exposure in children with allergic rhinitis.
Respir Med
November 2024
Department of Pediatric Allergy and Pulmonology, Celal Bayar University School of Medicine, Manisa, Turkey. Electronic address:
Objectives: Tobacco smoke exposure is associated with inflammatory changes in the respiratory system including nasal mucosa. Our aim was to demonstrate nasal mucosal inflammation such as neutrophilic activation and epithelial permeability in patients with allergic rhinitis with exposure to environmental tobacco smoke (ETS) and reveal its effect on allergic rhinitis symptoms.
Methods: We enrolled 204 subjects with allergic rhinitis to this cross-sectional study.
Sensing creatinine in urine via the iontronic response of enzymatic single solid-state nanochannels.
Biosens Bioelectron
January 2025
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CONICET, CC 16 Suc. 4, La Plata, B1904DPI, Argentina. Electronic address:
In this study, we investigate the integration of the enzyme creatinine deiminase into solid-state nanopore walls through electrostatic assembly for the development of creatinine sensors. In these asymmetric single nanochannels, ionic transport is determined by the surface charge inside the channel, resulting in diode-like behavior that rectifies ionic current. The efficiency of such rectification depends on the surface charge density.
View Article and Find Full Text PDFExtracellular Vesicle-Encapsulated microRNAs and Respiratory Health Among American Indian Participants in the Strong Heart Study.
Chest
August 2024
Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY.
Background: American Indian populations have experienced marked disparities in respiratory disease burden. Extracellular vesicle-encapsulated microRNAs (EV-miRNAs) are a novel class of biomarkers that may improve recognition of lung damage in indigenous populations in the United States.
Research Question: Are plasma EV-miRNAs viable biomarkers of respiratory health in American Indian populations?
Study Design And Methods: The Strong Heart Study is a prospective cohort study that enrolled American Indian patients aged 45 to 74 years.
Club cell protein (CC)16 as potential lung injury marker in a porcine 72 h polytrauma model.
Eur J Trauma Emerg Surg
December 2022
Experimental Radiology, Department of Radiology and Nuclear Medicine, Otto-von-Guericke University, 39120, Magdeburg, Germany.
Background: Polytrauma and respiratory tract damage after thoracic trauma cause about 25% of mortality among severely injured patients. Thoracic trauma can lead to the development of severe lung complications such as acute respiratory distress syndrome, and is, therefore, of great interest for monitoring in intensive care units (ICU). In recent years, club cell protein (CC)16 with its antioxidant properties has proven to be a potential outcome-related marker.
View Article and Find Full Text PDFSP-D and CC-16 Pneumoproteins' Kinetics and Their Predictive Role During SARS-CoV-2 Infection.
Front Med (Lausanne)
February 2022
Inflammation and Cell Death Signalling Group, Experimental Gastroenterology Laboratory and Endotools-Medical Faculty, ULB, Brussels, Belgium.
Background: Surfactant protein D (SP-D) and pulmonary club cell protein 16 (CC-16) are called "pneumoproteins" and are involved in host defense against oxidative stress, inflammation, and viral outbreak. This study aimed to determine the predictive value of these pneumoproteins on the incidence of acute respiratory distress syndrome (ARDS) or death in patients with coronavirus disease-2019 (COVID-19).
Methods: This retrospective study included 87 patients admitted to an emergency department.
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