The development of hydrotherapy in the first half of the XIX century is presented in short. The geographical, climatic and epidemiological situation of Druskininkai, a health resort founded in 1837 has been mentioned. The natural substances: salt springs and therapeutic muds are described sufficiently. The development of the health resort in the XIX and the first half of XX century has been recounted. The physicians Ksawery Wolfgang (?-1864), Ludwik Zembrzycki, Izydor Nahumowicz (1800-1842), Anicety Renier (1804-1877), Kazimierz Choiski (1814-1882), Jan Pilecki (1821-1878), Józef Markiewicz (1834-1923), Walery Bujakowski (1857-1919) and the others and local rich gentry played an important role in the development of Druskieniki. The physician was undoubtedly the most esteemed person-age of this health resort. Russification of this health resort on the turn of the XIX century is also presented. The role of Marshal J6zef Pitsudski in this development is pointed out. The comparison of the medical indications and contraindications in Druskininkai in the middle of the XIX century and in the thirties of the XX century are presented in more detail. The scale of medical indications was wide. Druskieniki was an important health resort in pre-war Poland.
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Microb Pathog
January 2025
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:
Following a period of disuse owing to the emergence of multidrug-resistant Gram-negative bacteria, colistin has regained global attention as an antibiotic of last resort. The resurgence in its utilization has led to a concurrent increase in acquired resistance, presenting a significant challenge in clinical treatment. Predominantly, resistance mechanisms involve alterations in the lipid A component of the lipopolysaccharide (LPS) structure.
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January 2025
Department of Medical Microbiology "Corr. Mem. Prof. Ivan Mitov, MD, DMSc", Faculty of Medicine, Medical University of Sofia, 2 Zdrave Str., 1431 Sofia, Bulgaria.
Linezolid is an oxazolidinone antibiotic and is considered a last-resort treatment option for serious infections caused by problematic Gram-positive pathogens, including vancomycin-resistant enterococci. The present study aimed to explore the linezolid resistance mechanisms and genomic characteristics of two vancomycin-susceptible isolates from Bulgaria. The strains designated Efs2503-bg (inpatient from Pleven) and Efs966-bg (outpatient from Varna) were recovered from wounds in 2018 and 2023, respectively.
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January 2025
Laboratório de Epidemiologia e Microbiologia Moleculares-LEMiMo, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos 13563-120, SP, Brazil.
KPC is a clinically significant serine carbapenemase in most countries, and its rapid spread threatens global public health. transmission is commonly mediated by Tn transposons. The gene has also been found in (NTE).
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Department of Physical Medicine, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.
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View Article and Find Full Text PDFRegul Toxicol Pharmacol
January 2025
Corteva Agriscience, Zuid-Oostsingel 24D, Bergen op Zoom, 4611 BB, the Netherlands.
Environmental Safety Assessments (ESA) are mandatory for several regulatory purposes and are an important component of stewardship/sustainability initiatives. Fish testing is used for assessing chemical toxicity and bioaccumulation potential; amphibians are included in some jurisdictions and their use is increasing to assess endocrine disruption. Alternative methods are becoming more available, covering the principles of the 3Rs (i.
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