A large number of diverse, complex, and distributed data resources are currently available in the Bioinformatics domain. The pace of discovery and the diversity of information means that centralised reference databases like UniProt and Ensembl cannot integrate all potentially relevant information sources. From a user perspective however, centralised access to all relevant information concerning a specific query is essential. The Distributed Annotation System (DAS) defines a communication protocol to exchange annotations on genomic and protein sequences; this standardisation enables clients to retrieve data from a myriad of sources, thus offering centralised access to end-users.We introduce MyDas, a web server that facilitates the publishing of biological annotations according to the DAS specification. It deals with the common functionality requirements of making data available, while also providing an extension mechanism in order to implement the specifics of data store interaction. MyDas allows the user to define where the required information is located along with its structure, and is then responsible for the communication protocol details.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441562 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044180 | PLOS |
BMC Med Educ
January 2025
Centro de Investigación de Educación Médica y Bioética - EDUCAB-UPT, Facultad de Ciencias de la Salud, Universidad Privada de Tacna, Tacna, Peru.
Background: Residency selection is crucial for enhancing the healthcare workforce. Most research on this topic arises from the global north, leaving a gap from the global south perspective. Hence, this study aimed to evaluate factors associated with the Peruvian National Residency Examination (ENARM) in Peruvian applicants.
View Article and Find Full Text PDFBMC Surg
January 2025
Global Surgery Division, Department of Surgery, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Climate change is an emerging global health crisis, disproportionately affecting low- and middle-income countries (LMICs) where health outcomes are increasingly compromised by environmental stressors such as pollution, natural disasters, and human migration. With a focus on promoting health equity, Global Surgery advocates for expanding access to surgical care and enhancing health outcomes, particularly in resource-limited and disaster-affected areas like LMICs. The healthcare industry-and more specifically, surgical care-significantly contributes to the global carbon footprint, primarily through resource-intensive settings, i.
View Article and Find Full Text PDFSci Rep
January 2025
Torrens University Australia, Fortitude Valley, QLD 4006, Leaders Institute, 76 Park Road, Woolloongabba, QLD 4102, Brisbane, Queensland, Australia.
Sensors (Basel)
December 2024
College of Cryptography Engineering, Engineering University of PAP, Xi'an 710086, China.
With the rapid development of the Internet of Things (IoT), the scope of personal data sharing has significantly increased, enhancing convenience in daily life and optimizing resource management. However, this also poses challenges related to data privacy breaches and holdership threats. Typically, blockchain technology and cloud storage provide effective solutions.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
Background: At the European level, several regulatory measures (ie, priority medicines (PRIME) scheme, accelerated assessment, conditional marketing authorisation and authorisation under exceptional circumstances) are in place with the aim to expedite the marketing authorisation process for medicines targeting unmet medical needs (UMNs). However, the potential impact of these measures on subsequent decisions regarding market access at the national level, and ultimately if medicines making use of these supporting measures reach the patient earlier, remains unclear.
Objectives: This study seeks to (1) assess the impact of such European regulatory measures on the number of successful applications and time to reimbursement of this group of medicines in the national context of Belgium and (2) evaluate the association between the application of European regulatory measures and Belgian measures (ie, early access pathways and managed entry agreements).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!