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Unintentional exposure to leuprolide acetate during early pregnancy with a huge intramural myoma.
BMJ Case Rep
January 2025
Department of Medicine, University of Hawai'i at Mānoa John A Burns School of Medicine, Honolulu, Hawaii, USA.
Leuprolide acetate is commonly used to reduce the size of myomas before surgery. Initially, it stimulates pituitary gonadotropin secretion, followed by sustained suppression of gonadal function. However, the impact on pregnancy outcomes from inadvertent exposure remains unclear.
View Article and Find Full Text PDFUPDATE ON MEDICAL TREATMENT OF ENDOMETRIOSIS: NEW DRUGS OR NEW THERAPEUTIC APPROACHES?
Gynecol Obstet Invest
December 2024
Background: No conceptually new drugs for the safe and successful cure of endometriosis are likely to become available soon. Hormonal modulation of ovarian function and suppression of menstruation remain the pillars of disease control. However, existing drugs may be used following novel modalities to limit the consequences of endometriosis progression.
View Article and Find Full Text PDFSurgical Treatment of a Rare Case of Extrapelvic Endometriosis in the Rectus Abdominis Muscles With Negative Imaging Findings: A Case Report and Mini Literature Review.
Cureus
November 2024
Department of Obstetrics and Gynecology, General Hospital of Trikala, Trikala, GRC.
Abdominal wall endometriosis is an uncommon clinical entity. The localization of the disease in the muscles of the abdominal wall is considered extremely rare. Our patient with two cesarean sections in her obstetric history presented to the gynecology outpatient clinic of the General Hospital of Trikala, Trikala, Greece, complaining of intense pain, particularly during menstruation, though no palpable lesions were found in the abdominal wall.
View Article and Find Full Text PDFAssessing Practice Patterns Regarding Use of Norethindrone Acetate in Adolescents.
J Pediatr Adolesc Gynecol
December 2024
Division of Adolescent Medicine, Department of Pediatrics, Indiana University School of Medicine, Indianapolis.
Background: Norethindrone acetate (NETA) is commonly used in adolescent patients for management of heavy menstrual bleeding, menstrual suppression, and endometriosis. Clinical guidelines do not address specific dosing strategies, clinical indications, contraindications, or monitoring. We sought to survey current prescribers of NETA to assess practice patterns of use among adolescent patients.
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