The crystal structure of the decamer sequence d(CCGGGACCGG)(4) has previously been reported at 2.16 Å resolution as a four-way junction. Here, the structure of this sequence is reported at the significantly higher resolution of 1.6 Å, which is the highest resolution reported for a four-way junction. This allowed the unambiguous identification of an extensive hydration network with distinct patterns and solvent-mediated interactions that shed new light on the role of water in the formation and stabilization of junction structures.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497973 | PMC |
| http://dx.doi.org/10.1107/S1744309112034926 | DOI Listing |
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