In the pediatric population, malignant osseous tumors of the spine include osteosarcoma, Ewing sarcoma, lymphoma, and metastatic neuroblastoma. Although these tumors are rare, prompt diagnosis and recognition are critical to the overall prognosis. Improved understanding of the natural history of spine deformity, combined with advances in imaging, surgical technology, radiation therapy, and chemotherapeutic regimens, has improved survival rates and decreased rates of local recurrence-especially recurrence of low-grade lesions. Prognosis for patients with high-grade lesions with distant metastasis on presentation remains exceedingly poor. Recognition of these spine tumors and prompt referral to a tertiary care center that specializes in oncology can optimize patient outcomes.
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http://dx.doi.org/10.5435/JAAOS-20-10-646 | DOI Listing |
Sci Rep
January 2025
Department of Haematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Staszica Street 11, 20-081, Poland.
Mastocytosis is a heterogeneous group of disorders, characterized by accumulation of clonal mast cells which can infiltrate several organs, most often spine (70%). The pathogenesis of mastocytosis bone disease is poorly understood. The main aim of the study was to investigate whether neoplastic mast cells may be the source of sclerostin and whether there is an association between sclerostin and selected bone remodeling markers with mastocytosis related bone disease.
View Article and Find Full Text PDFAnticancer Res
January 2025
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, U.S.A.;
Background/aim: Scapular osteosarcoma is a rare malignancy, and the understanding of its optimal treatment strategies and long-term outcomes remains limited. The purpose of the current study was to evaluate our institutional experience.
Patients And Methods: We reviewed 14 patients (8 females, 5 males; mean age 44±17 years) treated for scapular osteosarcoma from 1985 to 2022.
Acta Neurochir (Wien)
December 2024
Department of Spine Surgery, Zentralklinik Bad Berka, Bad Berka, Germany.
Purpose: This study introduces a retrospective analysis of the surgical management of 213 consecutive cases of cervical spine metastases and Multiple Myeloma Cases.
Materials And Methods: Retrospective analysis of prospectively collected data in a single surgical center of patients who underwent surgery for tumors of the cervical spine between 1994 and 2017. Exclusion criteria were intradural tumors and primary tumors.
Sci Rep
December 2024
Department of Oral Medicine and Radiology, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
A novel classification system, termed the Sivan classification, was developed to enhance the diagnosis of jaw lesions by utilizing visual volumetric analysis of three-dimensional Cone Beam Computed Tomography (CBCT) images. This classification groups lesions into ten categories, primarily divided into hypovolumetric, hypervolumetric, and normovolumetric groups. To validate this system, 10 raters-comprising 5 general dentists and 5 oral radiology specialists-assessed the CBCT images and diagnosed the lesions using the Sivan classification.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2024
Department of Otolaryngology-Head and Neck Surgery, Naso-Orbital-Maxilla and Skull Base Center, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou510630, China.
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