AI Article Synopsis
- The text discusses the creation of bio-inorganic protocells that can mimic some functions of living cells by assembling a network similar to a cytoskeleton and performing chemical reactions.
- It highlights the use of semi-permeable membranes that allow certain molecules to pass through, enabling the protocells to maintain an internal reaction space.
- The enzymatic activity within these protocells can be adjusted by reversing the disassembly of a hydrogel, which is made from amino acids, located inside the cells.
Article Abstract
The fabrication of enzymatically active, semi-permeable bio-inorganic protocells capable of self-assembling a cytoskeletal-like interior and undergoing small-molecule dephosphorylation reactions is described. Reversible disassembly of an amino acid-derived supramolecular hydrogel within the internalized reaction space is used to tune the enzymatic activity of the nanoparticle-bounded inorganic compartments.
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| http://dx.doi.org/10.1002/smll.201201539 | DOI Listing |
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