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A Case Report of Extra-pericardial Tamponade From a Low-Level Fall.
Cureus
November 2024
Cardiothoracic Surgery, Mater Misericordiae University Hospital, Dublin, IRL.
Article Synopsis
- A 61-year-old man with a history of COPD, ongoing anticoagulant therapy, and pneumonia was admitted to the emergency department in critical condition due to chest pain and shortness of breath.
- A chest X-ray and CT scan revealed a large mediastinal hematoma, rib fractures, and significant blood loss requiring urgent reversal of his anticoagulant medication before surgery.
- After an emergency sternotomy to evacuate the hematoma, the patient made a full recovery, highlighting the importance of imaging in older patients with fall-related injuries and the need for careful management of anticoagulants.
Evaluation of BBIBP-CorV Sinopharm COVID-19 vaccine effectiveness in Sri Lanka: a test-negative case control study.
BMJ Open
November 2024
State Pharmaceuticals Corporation of Sri Lanka, Colombo, Sri Lanka.
Objectives: There is limited research on real-world effectiveness of BBIBP-CorV Sinopharm COVID-19 vaccine. This study evaluated real-world effectiveness of Sinopharm vaccine in Sri Lanka by assessing absolute vaccine efficacy.
Design And Setting: A retrospective test-negative case-control study was conducted at ten large government hospitals across the country.
Association of Anabolic Steroid Use With Hypertension and Cardiomyopathy: A Case Study.
Cureus
October 2024
Internal Medicine, Sound Physicians/Montefiore Nyack Hospital, Nyack, USA.
Article Synopsis
- * A case study discusses a 46-year-old man who experienced complications like swelling, bruising, and shortness of breath due to AAS use, revealing underlying issues like high blood pressure and heart failure.
- * The case highlights the importance of screening for heart and vascular health in individuals using anabolic steroids, as they may not exhibit clear symptoms of underlying heart conditions.
The Chinese Herbal Medicine Li Qi Huo Xue Di Wan Ameliorates Ischemia or Hypoxia-Induced Cardiac Injury and Remodeling in the Heart Through a Mechanism Involving Reduction of Necroptosis.
Environ Toxicol
November 2024
Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
Li Qi Huo Xue Di Wan (LQHXDW), a Chinese herbal medicine, is commonly used to treat symptoms such as palpitations, chest tightness, chest pain, and shortness of breath. However, its potential to reduce ischemia or hypoxia-induced cardiac injury and remodeling, along with the precise mechanisms involved, remains unclear. This study aims to investigate the effects of LQHXDW on cardiac injury and remodeling induced by ischemia or hypoxia, both in vivo and in vitro, and to elucidate the underlying mechanisms.
View Article and Find Full Text PDFChronic obstructive pulmonary disease's eosinophilic phenotype: Clinical characteristics, biomarkers and biotherapy.
Eur J Intern Med
January 2025
Istituti Clinici Scientifici Maugeri IRCCS, Pulmonary Rehabilitation Unit of Telese Terme Institute, Italy.
COPD is a chronic, heterogeneous inflammatory disorder of the airways with persistent and poorly reversible airflow limitation, causing symptoms such as cough, shortness of breath, and sputum production. Despite optimal treatment, some patients remain symptomatic due to the disease's heterogeneity, manifesting in various phenotypes. One notable phenotype involves eosinophilic inflammation, with a variable prevalence.
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