Objective: To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.
Methods: Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.
Results: Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.
Conclusion: Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.
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| http://dx.doi.org/10.3967/0895-3988.2012.04.003 | DOI Listing |
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