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Introduction: In vitro studies show that fluoride varnishes (FV) differ significantly in their ability to remineralize and fluoridate enamel caries lesions, as respectively measured by surface microhardness recovery (%SMHr) and enamel fluoride-uptake (EFU). However, there is a need to confirm these findings in clinically relevant conditions.
Methods: This in situ study adopted a five-leg cross-over design.
Phantom Tumor: A Diagnostic Challenge.
Cureus
February 2025
Internal Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
The vanishing or phantom tumor of the lung is an uncommon condition that is caused by an interlobar pleural collection of transudative fluid, resulting from pulmonary congestion. The diagnosis is typically made via chest X-ray, where it appears as a nodular opacity, often mistaken for a pulmonary tumor, hence the term "phantom tumor." This condition is most frequently associated with systemic diseases such as heart failure or chronic kidney disease.
View Article and Find Full Text PDFOptimized Lightweight Architecture for Coronary Artery Disease Classification in Medical Imaging.
Diagnostics (Basel)
February 2025
Department of Computer Engineering, Gachon University Sujeong-Gu, Seongnam-si 13120, Republic of Korea.
: The early and accurate detection of Coronary Artery Disease (CAD) is crucial for preventing life-threatening complications, particularly among athletes engaged in high-intensity endurance sports. This demographic faces unique cardiovascular risks, as prolonged and intense physical exertion can exacerbate underlying CAD conditions. Studies indicate that while athletes typically exhibit enhanced cardiovascular health, this demographic is not immune to Coronary Artery Disease (CAD) risks.
View Article and Find Full Text PDFEvaluation of the predictive value of CSF-restricted oligoclonal bands on residual disability and risk of relapse in adult patients with MOGAD: MOGADOC study.
Mult Scler
January 2025
Service de Neurologie, Sclérose en Plaques, Pathologie de la Myéline et Neuro-Inflammation, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France.
Background: The clinical course of myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is variable. However, robust markers of poor outcome and/or relapse risk are still missing.
Objective: To evaluate the frequency of cerebrospinal fluid-restricted oligoclonal bands (CSF-OCB) in a national cohort of adult MOGAD patients and to assess their prognostic value for the risk of relapse and severity.
Adult-onset vanishing white matter disease due to a novel compound heterozygous EIF2B2 mutation: a case report and brief review.
Neurol Sci
January 2025
Department of Neurology, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Background And Objectives: Vanishing white matter disease (VWMD) is an autosomal recessive leukoencephalopathy caused by mutations in the EIF2B1-5 genes, typically rare in adulthood. We present a case of adult-onset VWMD with a novel EIF2B2 mutation.
Methods: We collected the patient's clinical data, cerebrospinal fluid (CSF) results, laboratory tests, imaging features, genetic analysis, and follow-up data over a 4-year period.
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