AI Article Synopsis
- Biomaterial-associated infections can happen with both permanent and temporary medical devices used in the body.
- Despite their growing use, there aren't many biomaterials made specifically to prevent these infections effectively.
- The review offers design guidelines focused on balancing the integration of host cells and minimizing bacterial attachment on the surfaces of these biomaterials.
Article Abstract
Biomaterial-associated infections occur on both permanent implants and temporary devices for restoration or support of human functions. Despite increasing use of biomaterials in an aging society, comparatively few biomaterials have been designed that effectively reduce the incidence of biomaterial-associated infections. This review provides design guidelines for infection-reducing strategies based on the concept that the fate of biomaterial implants or devices is a competition between host tissue cell integration and bacterial colonization at their surfaces.
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| http://dx.doi.org/10.1126/scitranslmed.3004528 | DOI Listing |
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Article Synopsis
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