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Magnesium sulfate for fetal neuroprotection in preterm labor: an updated systematic review and meta-analysis of randomized controlled trials.
Arch Gynecol Obstet
December 2024
Unit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127, Palermo, Italy.
Objective: Antenatal magnesium sulfate has been reported to reduce the risk of neurological impairment in fetuses born to women at risk of preterm labor. However, the evidence to support its use is conflicting. We conducted this meta-analysis to assess the efficacy and safety of magnesium sulfate in women at risk of preterm labor as new research is available from RCTs giving insights into MgSO4 treatment among differing gestational age groups.
View Article and Find Full Text PDFA review of clinical practice guidelines on the management of preeclampsia and nursing inspiration.
Int J Nurs Sci
November 2024
School of Nursing, Peking University, Beijing, China.
Objectives: To review, evaluate, and synthesize the recommendations of guidelines on preeclampsia (PE) from a nursing perspective.
Methods: This is a systematic review of international and national guidelines on PE. Electronic databases and related guideline websites were searched from 2013 to 2023.
Implementation of maternal death audits and changes in maternal health care in Cambodia, 2010-2017.
Western Pac Surveill Response J
December 2024
World Health Organization Regional Office for the Western Pacific, Manila, Philippines.
Objective: Cambodia is one of seven countries globally that met Millennium Development Goal 5A: reduction of maternal deaths by at least 75% between 1990 and 2015. The maternal death audit (MDA) was instituted in 2004 to support the improvement of maternal care. We evaluated progress in MDA implementation and maternal health services in Cambodia between 2010 and 2017.
View Article and Find Full Text PDFClinical Guidelines for Management of Infants Born before 25 Weeks of Gestation: How Representative Is the Current Evidence?
J Pediatr
November 2024
Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia; Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia; Department of Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.
Article Synopsis
- - The study evaluates if major management guidelines for extremely preterm infants are effectively applicable to those born before 25 weeks' gestation by reviewing three significant sets of guidelines and their referenced studies.
- - Out of 519 studies analyzed, only about 14.5% of infants were under 25 weeks, with a significant portion of the research, 37.8%, not including any infants from this critical group.
- - The findings conclude that infants born before 25 weeks gestation are underrepresented in the data driving clinical guidelines, highlighting the need for more focused research on this vulnerable population.
Post-Asphyxial Aftercare and Management of Neonates in Low- and Middle-Income Countries: A Systematic Evidence Synthesis.
Neonatology
November 2024
Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Introduction: Effective post-resuscitation care is crucial for improving outcomes in neonates post-asphyxia. This review aimed to provide a comprehensive overview of post-asphyxial aftercare strategies and forms part of a supplement describing an extensive synthesis of effective newborn interventions in low- and middle-income countries (LMICs).
Methods: Evidence was generated by performing de novo reviews, updates to reviews via systematic searches, and reanalyses of studies conducted in LMICs from existing reviews.
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