A five-year-old, female, neutered boxer, with neuroanatomical signs consistent with a C1-C5 myelopathy, was diagnosed with a prosencephalic mass and associated severe cervicothoracic syringohydromyelia. After treatment with corticosteroids and lomustine, neurological examination was normal. Imaging repeated three months later showed significant reduction in both the size of the mass and the syringohydromyelia. To the authors' knowledge, this is the first reported case of a dog with syringohydromyelia secondary to a rostral brain mass that had clinical signs on presentation solely due to the syrinx, and the first reported case in a dog of partial resolution of syringohydromyelia after treatment solely with chemotherapy.
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http://dx.doi.org/10.1111/j.1748-5827.2012.01266.x | DOI Listing |
Childs Nerv Syst
February 2022
Department of Neurosurgery, Rush University Medical Center, Chicago, IL, USA.
Objective: Cervical kyphosis is rare in the pediatric population. It may be syndromic or acquired secondary to laminectomy, neoplasia, or trauma. Regardless, this should be avoided to prevent progressive spinal deformity and neurological deficit.
View Article and Find Full Text PDFAsian J Neurosurg
January 2017
Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Hemangiomas have rarely been found in the spinal cord. A few cases of spinal capillary hemangioma have been reported since 1987. The authors reported the two cases of capillary hemangioma including the tumor at conus medullaris and the another mimicked von Hippel-Lindau disease.
View Article and Find Full Text PDFHum Genome Var
December 2016
Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA; Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.
and its paralog encode phosphatidylinositol 5-phosphatases that localize to the primary cilium and have roles in ciliogenesis. Mutations in cause the X-linked Dent disease type 2 (DD2; OMIM# 300555), characterized by low-molecular weight proteinuria, hypercalciuria, and the variable presence of cataracts, glaucoma and intellectual disability without structural brain anomalies. Disease-causing mutations in have not been described in humans.
View Article and Find Full Text PDFJ Neurol Surg Rep
August 2014
Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio, United States.
We present the case of a 55-year-old woman with diffuse adhesive arachnoiditis in the posterior fossa and cervicothoracic spine following posterior inferior cerebellar artery aneurysmal subarachnoid hemorrhage (SAH). She underwent aneurysm clipping with subsequent gradual neurologic decline associated with sensory disturbances, gait ataxia, and spastic paraparesis. Magnetic resonance imaging revealed diffuse adhesive arachnoiditis in the posterior fossa and cervicothoracic spine, syringobulbia, and multiple arachnoid cysts in the cervicothoracic spine along with syringohydromyelia.
View Article and Find Full Text PDFJ Small Anim Pract
October 2012
Southern Counties Veterinary Specialists, Hangersley, Ringwood, Hampshire.
A five-year-old, female, neutered boxer, with neuroanatomical signs consistent with a C1-C5 myelopathy, was diagnosed with a prosencephalic mass and associated severe cervicothoracic syringohydromyelia. After treatment with corticosteroids and lomustine, neurological examination was normal. Imaging repeated three months later showed significant reduction in both the size of the mass and the syringohydromyelia.
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