Objectives: The ability to perceive high spatial frequencies (i.e., fine detail) is impaired when contours are placed near the detail to be resolved (Bouma, H. [1970]. Interaction effects in parafoveal letter recognition. Nature, 226, 177-178. doi:10.1038/226177a0; Flom, M. C., Weymouth, F. W., & Kahneman, D. [1963]. Visual resolution and contour interaction. Journal of the Optical Society of America A, 53, 1026-1032. doi:10.1364/JOSA.53.001026.). This visual crowding is more pronounced outside of central vision and may be more pronounced in older adults. Thus, the motivation for the present study.
Method: Younger (M = 20.95 years) and older adults (M = 70.32 years) detected gap orientation in a Landolt C presented at 3° or 6° either alone or flanked by bars of the same spatial scale.
Results: Both age groups demonstrated a visual crowding effect, in that acuity deteriorated in the flanking condition, an effect that grew with eccentricity. Older adults exhibited a larger crowding effect, particularly at 6°. Younger adults tested at reduced illumination did not show the crowding effect of older adults. Thus, age differences do not appear to result from reduced retinal illumination. When the crowding effect was operationalized as the ratio of crowded to uncrowded acuity, age differences were eliminated at both 3° and 6°.
Discussion: These data have implications for understanding age differences in functional vision, including reading and visual search.
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http://dx.doi.org/10.1093/geronb/gbs086 | DOI Listing |
J Biomech
January 2025
Grado Department of Industrial and Systems Engineering, Virginia Tech, 250 Durham Hall (0118), 1145 Perry Street, Blacksburg, VA 24061, USA. Electronic address:
Deficient trip recovery kinematics have been implicated in many trip-induced falls. Three key requisites for successful trip recovery include limiting trunk flexion, maintaining adequate hip height to enable repeated stepping, and completing recovery steps to extend the base of support. The purpose of this study was to evaluate sternum drop as a new measure of trip recovery performance.
View Article and Find Full Text PDFGen Hosp Psychiatry
December 2024
School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430061, China; Department of Geriatrics, Hubei Provincial Hospital of Traditional Chinese Medicine (Affiliated Hospital of Hubei University of Chinese Medicine), Wuhan 430060, China. Electronic address:
Background: Depression and anxiety are prevalent among older adults. However, most older adults have poor access to age-specific mental health services. While Information technology-based Cognitive Behavioral Therapy (ICBT) has shown promise as an accessible alternative to face-to-face interventions, its effectiveness specifically within the older adults warrants further investigation.
View Article and Find Full Text PDFObjective: Elevated blood pressure (BP), even at prehypertensive levels, increases cardiovascular disease risk among people with HIV (PWH); yet international guidelines in low-income countries recommend treatment initiation at BP at least 140/90 mmHg. We determined the efficacy, feasibility, and acceptability of treating prehypertension in PWH in Haiti.
Design: An unblinded randomized clinical trial (enrolled April 2021-March 2022) with 12-month follow-up.
Ann Intern Med
January 2025
Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan (K.K.).
Background: Dialysis patients have high rates of fracture morbidity, but evidence on optimal management strategies for osteoporosis is scarce.
Objective: To determine the risk for cardiovascular events and fracture prevention effects with denosumab compared with oral bisphosphonates in dialysis-dependent patients.
Design: An observational study that attempts to emulate a target trial.
Ann Intern Med
January 2025
Center for Healthcare Delivery Sciences, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (R.J.D., N.K.C., N.H., J.C.L.).
Background: The evidence informing the harms of gabapentin use are at risk of bias from comparing users with nonusers.
Objective: To describe the risk for fall-related outcomes in older adults starting treatment with gabapentin versus duloxetine.
Design: New user, active comparator study using a target trial emulation framework.
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