Bilateral asynchronous renal cell carcinoma with metastatic involvement of the tongue.

Case Rep Pathol

Maxillofacial Unit, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead RH19 3DZ, UK ; Regional Maxillofacial Unit, Aintree University Hospital, Lower Lane, Liverpool L9 7AL, UK.

Published: September 2012

AI Article Synopsis

  • Renal cell carcinoma (RCC) is known for spreading to distant organs and can involve both kidneys, even years after initial treatment.
  • A rare case of bilateral RCC was reported, where a tongue lesion was the first sign of cancer spread, found 14 years after the left kidney was removed.
  • Due to the patient's other health issues, immunotherapy was not an option, so surgeons removed the tongue lesion to ease symptoms and prevent complications, but the patient unfortunately died five months later.

Article Abstract

Renal cell carcinoma (RCC) has a propensity for distant organ metastasis and late recurrence, involving not only the ipsilateral but also contralateral kidney. Lingual metastasis by RCC is rare. We present an unusual case of bilateral asynchronous RCC. Involvement of the right kidney was discovered only after a metastatic tongue lesion was diagnosed. The original RCC had been treated by left nephrectomy 14 years previously. Due to end-stage primary pulmonary malignancy, and poor function of the remaining kidney, immunotherapy was unsuitable. Palliative local resection of the lingual metastasis alleviated functional difficulties and was preventative against airway obstruction, but the patient died five months later.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447327PMC
http://dx.doi.org/10.1155/2012/729642DOI Listing

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