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Rome Foundation Working Team Report on overlap in disorders of gut-brain interaction.
Nat Rev Gastroenterol Hepatol
January 2025
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
In patients with disorders of gut-brain interaction (DGBI), overlapping non-gastrointestinal conditions such as fibromyalgia, headaches, gynaecological and urological conditions, sleep disturbances and fatigue are common, as is overlap among DGBI in different regions of the gastrointestinal tract. These overlaps strongly influence patient management and outcome. Shared pathophysiology could explain this scenario, but details are not fully understood.
View Article and Find Full Text PDFRelationship Between ABO Blood Groups and Mental Disorders.
J Blood Med
January 2025
Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Previous research has unveiled an intriguing positive association between the AB blood group and mental disorders in general. In this study, we compared ABO blood groups with five major groups of mental disorders to attain a higher level of specificity. The analyses were conducted using data from the CoLaus|PsyCoLaus study (N=5111).
View Article and Find Full Text PDFPharmacological interventions for patients with chronic primary musculoskeletal pain: disparity between synthesized evidence and real-world clinical practice.
Pain Rep
February 2025
Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Article Synopsis
- Chronic primary musculoskeletal pain (CPMP) significantly impacts public health, with many clinical trials focusing on pharmacological treatments that may not reflect actual clinical situations.
- This study compared a clinical sample of 103 CPMP patients from healthcare records to a larger randomized controlled trial (RCT) sample of 8,665 participants, analyzing demographic data and medications used.
- Findings revealed significant differences in medication distribution between the two groups, highlighting a gap between research and real-world treatment, emphasizing the need for further studies addressing the role of psychiatric comorbidities in CPMP management.
Short-Term Outcome of Patients in Delirium at Medical Intensive Care Unit.
J Nepal Health Res Counc
October 2024
Department of Humanities and Social Sciences, Tribhuvan University, Kathmandu, Nepal.
Background: Delirium is highly prevalent in the Intensive Care Unit (ICU), and managing it in critically ill patients with severe comorbidities is challenging due to transient nature of symptoms. However its significance is underestimated, often overlooked and misdiagnosed by healthcare providers. In Nepal, limited studies has been done on delirium in medical ICUs hence this study aims to assess short-term outcome of admitted patients in delirium.
View Article and Find Full Text PDFRecombinant human leptin for the treatment of anorexia nervosa.
Lancet
October 2024
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:
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