Using in situ imaging, we report surface fold formation and fluidlike flow instabilities in sliding of annealed copper. We demonstrate using simulations that folding is principally driven by grain-induced plastic instability. The phenomenon shows remarkable similarities with Kelvin-Helmholtz-type flow instabilities in fluids. While such instabilities have been conjectured to exist in sliding interfaces at the nanoscale, we find vortices and folding in metals at the mesoscale. The occurrence of folds impacts many applications, including surface generation processes and tribology.
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http://dx.doi.org/10.1103/PhysRevLett.109.106001 | DOI Listing |
Environ Mol Mutagen
December 2024
GENOTOX Laboratory, São Paulo State University (UNESP), Medical School, Botucatu, Brazil.
Sevoflurane is an inhalation anesthetic widely used for general anesthesia, but its genotoxic potential is controversial in clinical studies. It is unknown whether the effects are due to surgery or the anesthetic. Thus, for the first time, the present study investigated genotoxicity in peripheral blood cells and in target organs (liver, lung, and kidney) and micronucleus (MN) in the bone marrow of a single exposure to sevoflurane at three different concentrations in monitored mice.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
TU Berlin University: Technische Universitat Berlin, Fachbereich Keramische Werkstoffe, Hardenbergstr. 40, 10623, Berlin, GERMANY.
Carbon dioxide hydrogenation to methanol is a key chemical reaction to store energy in chemical bonds, using carbon dioxide as an energy sink. Indium oxide is amongst the most promising candidates for replacing the copper and zinc oxide catalyst, which is industrially applied for syngas mixtures but less idoneous for educts with carbon dioxide due to instability reasons. The polymorph of indium oxide and the operating conditions remain to be optimized for optimal and stable performance.
View Article and Find Full Text PDFUltrason Sonochem
December 2024
School of Energy and Power Engineering, Xi'an Jiaotong University, Xi'an 710049, China; MOE Key Laboratory of Cryogenic Technology and Equipment, Xi'an Jiaotong University, Xi'an 710049, China.
Cavitation plays a crucial role in the reliability of components in refrigeration systems. The properties of refrigerants change significantly with temperature, thereby amplifying the impact of thermodynamic effects. This study, based on the Large Eddy Simulation (LES) method and the Schnerr-Sauer (S-S) cavitation model, investigates the transient cavitating flow characteristics of the R134a refrigerant in a Venturi tube (VT).
View Article and Find Full Text PDFSLAS Discov
December 2024
Zhejiang Provincial Key Laboratory of Biometrology and Inspection and Quarantine, College of Life Science, China Jiliang University, Hangzhou, 310018, China. Electronic address:
Neuron-specific enolase (NSE) is currently the most reliable biomarker for small cell lung cancer (SCLC), which is important for disease monitoring, clinical evaluation and diagnosis. However, traditional methods suffer from various disadvantages, including instability, complexity, time-consuming operations, and the necessity for standards. In this study, we developed a calibration-free concentration analysis (CFCA) method based on surface plasmon resonance (SPR) technology, to accurately quantify the active concentration of NSE without relying on any standards.
View Article and Find Full Text PDFAm J Emerg Med
December 2024
Department of Emergency Medicine, Rush University Medical Center, Chicago, IL, USA.
Introduction: Several life-threatening conditions associated with thrombosis include acute ischemic stroke (AIS), acute myocardial infarction (AMI), and acute pulmonary embolism (PE). Fibrinolytics are among the treatment algorithms for these conditions.
Objective: This narrative review provides emergency clinicians with an overview of fibrinolytics for AIS, AMI, and PE in the emergency department (ED) setting.
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