AI Article Synopsis

  • The study aimed to see if inherited thrombophilia raises the risk of pre-eclampsia (PE) or affects its progression.
  • Researchers analyzed 50 women with severe PE and compared them to 50 healthy pregnant women for signs of inherited thrombophilia.
  • The findings showed no significant link between inherited thrombophilia and pre-eclampsia, indicating that these conditions are not associated.

Article Abstract

Objective: The aim was to determine whether inherited thrombophilia increases the risk of pre-eclampsia (PE) or interferes with its clinical course.

Material And Methods: We included 50 patients with severe PE and 50 healthy pregnant women. Patients were evaluated for inherited thrombophilia.

Results: Fourteen patients in the study group was factor V Leiden (FVL) carrier while it was 12% in the control group. In women with PE, FVL and other inherited thrombophilic factors were not more prevalent than in the controls.

Conclusion: The present study failed to demonstrate an association between the inherited thrombophilias and PE.

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Source
http://dx.doi.org/10.3109/15513815.2012.721475DOI Listing

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