Varicocele in younger as risk factor for inguinal hernia and for chronic venous disease in older: preliminary results of a prospective cohort study.

Background: Varicocele, inguinal hernia, and chronic venous insufficiency are often associated. Varicocele has its maximum prevalence in younger age, whereas hernia and chronic venous disease appear later. The aim of this study was to analyze the relationship between these conditions.

Methods: A prospective cohort study was conducted, consisting of two groups of male patients. Group A comprised patients with varicocele, whereas group B comprised those with problems other than varicocele. Both groups were followed over time and were assessed for the onset of signs and symptoms related to inguinal hernia and chronic venous disease.

Results: Preliminary results showed a positive correlation between the presence of varicocele in younger and the possible risk of hernia and/or chronic venous disease in later age.

Conclusions: Preliminary results suggest that varicocele in younger age appears to be an early marker of progression for a connective tissue-related disease in later age.