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Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function.
PLoS One
January 2025
Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.
T-cell response plays an important role in SARS-CoV-2 immunogenicity. For people living with HIV (PWH) and solid organ transplant (SOT) recipients there is limited evidence on the reliability of commercially available T-cell tests. We assessed 173 blood samples from 81 participants (62 samples from 35 PWH; 111 samples from 46 SOT recipients [lung and kidney]) with two commercial SARS-CoV-2 Interferon-γ (IFN-γ) release assays (IGRA; SARS-CoV-2 IGRA by Euroimmun, and IGRA SARS-CoV-2 by Roche).
View Article and Find Full Text PDFBuffExDb: web-based tissue-specific gene expression resource for breeding and conservation programmes in Bubalus bubalis.
Database (Oxford)
January 2025
Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Amidst the global challenge of extreme poverty, the livestock sector can significantly contribute to global sustainable development goals by enhancing resilience, smallholder productivity, and market participation. The Indian livestock sector is one of the largest in the world with a total livestock population of 535.82 million, ∼10.
View Article and Find Full Text PDFDistributed lag models for retrospective cohort data with application to a study of built environment and body weight.
Biometrics
January 2025
Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, United States.
Distributed lag models (DLMs) estimate the health effects of exposure over multiple time lags prior to the outcome and are widely used in time series studies. Applying DLMs to retrospective cohort studies is challenging due to inconsistent lengths of exposure history across participants, which is common when using electronic health record databases. A standard approach is to define subcohorts of individuals with some minimum exposure history, but this limits power and may amplify selection bias.
View Article and Find Full Text PDFA comparative analysis of perceptual noise in lateral and depth motion: Evidence from eye tracking.
J Vis
January 2025
Vision and Control of Action (VISCA) Group, Department of Cognition, Development and Psychology of Education, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia, Spain.
The characterization of how precisely we perceive visual speed has traditionally relied on psychophysical judgments in discrimination tasks. Such tasks are often considered laborious and susceptible to biases, particularly without the involvement of highly trained participants. Additionally, thresholds for motion-in-depth perception are frequently reported as higher compared to lateral motion, a discrepancy that contrasts with everyday visuomotor tasks.
View Article and Find Full Text PDFPhotooxidation Cross-Linked, Glutaraldehyde Cross-Linked, or Enzyme and Hydrostatic Pressure Processed Decellularized Biomaterials for Cardiovascular Repair Do Not Affect Host Response in a Rat Right Ventricular Outflow Flow Tract Reconstruction (RVOT) Model.
J Biomed Mater Res B Appl Biomater
February 2025
McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA.
Cardiovascular diseases (CVDs) were responsible for approximately 19 million deaths in 2020, marking an increase of 18.7% since 2010. Biological decellularized patches are common therapeutic solutions for CVD such as cardiac and valve defects.
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