AI Article Synopsis
- A 57-year-old man with gastric cancer underwent surgery but later developed acute pain and was found to have multiple liver tumors diagnosed as metastases.
- He started systemic chemotherapy with S-1 and cisplatin after the liver tumors were deemed unresectable, leading to significant tumor reduction after 8 courses.
- Following chemotherapy, he had surgery on the liver, and pathology showed no cancer cells, indicating a complete response to the treatment, suggesting chemotherapy is an effective option for unresectable liver metastases from gastric cancer.
Article Abstract
A57 years old man with gastric cancer underwent distal gastrectomy (pT3N1M0, pStage II B). Three months after gastric resection, he was admitted to our hospital because of acute right dorsal pain. Abdominal computed tomography showed multiple liver tumors with subcapsular hemorrhage. He was diagnosed as multiple liver metastases from gastric cancer. We judged liver tumors to be unresectable and decided to start systemic chemotherapy with S-1 and cisplatin (CDDP) because he was hemodynamically stable. After 8 courses of chemotherapy, the liver tumors were markedly reduced and judged as clinical partial response. Left hepatectomy and S5, S6, S7 partial hepatectomy for liver metastasis was performed. Histopathological examination of the resected specimen revealed no cancer cell in the liver, suggesting a pathologically complete response. We consider that systemic chemotherapy is one of the effective treatments for unresectable liver metastasis with subcapsular hemorrhage from gastric metastasis.
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