Sexual function in older women after oophorectomy.

Objective: To compare the sexual function of older women who had bilateral oophorectomy with that of older women who had retained their ovaries.

Methods: This cross-sectional study involved analysis of 1,352 women aged 57 to 85 years from the National Social Life, Health, and Aging Project. Women with previous bilateral oophorectomy were compared with women who retained their ovaries. The primary outcome of interest was self-report of sexual ideation, chosen because having thoughts about sexual experiences is not prohibited by either a partner or a woman's own physical limitations.

Results: Three hundred fifty-six (25.8%) women reported previous bilateral oophorectomy. Our analysis achieved 90% power to detect a difference of 10% in sexual ideation. No significant difference in the report of sexual ideation was found between women with previous bilateral oophorectomy and women who retained their ovaries (54.5% and 95% confidence interval [CI] 48.1-61.0 compared with 49.9% and 95% CI 45.3-54.5, P=.230), even after adjusting for current hormone therapy, age, education, and race (adjusted odds ratio 1.32, 95% CI 0.96-1.80).

Conclusion: Bilateral oophorectomy may not play a pivotal role in sexual ideation and function among older women.

Level Of Evidence: II.